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Alya G. Venyaminova
Researcher at Russian Academy of Sciences
Publications - 133
Citations - 1565
Alya G. Venyaminova is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: RNA & Oligonucleotide. The author has an hindex of 19, co-authored 131 publications receiving 1258 citations. Previous affiliations of Alya G. Venyaminova include Centre national de la recherche scientifique & National Museum of Natural History.
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Journal ArticleDOI
Fluorescent Probes for Nucleic Acid Visualization in Fixed and Live Cells
Alexandre S. Boutorine,D. S. Novopashina,Olga A. Krasheninina,Karine Nozeret,Alya G. Venyaminova +4 more
TL;DR: This review analyses the literature concerning non-fluorescent and fluorescent probes for nucleic acid imaging in fixed and living cells from the point of view of their suitability for imaging intracellular native RNA and DNA.
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Selective protection of nuclease-sensitive sites in siRNA prolongs silencing effect.
Anton A. Volkov,Natal’ya S. Kruglova,Mariya I. Meschaninova,Alya G. Venyaminova,Marina A. Zenkova,Valentin V. Vlassov,Elena L. Chernolovskaya +6 more
TL;DR: This study showed that the targeted chemical modification of nuclease-sensitive sites could provide highly efficient siRNA-based therapeutics for the control of disease-related genes.
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Aptamers against pathogenic microorganisms.
Anna Davydova,M. A. Vorobjeva,Dmitrii V. Pyshnyi,Sidney Altman,Valentin V. Vlassov,Alya G. Venyaminova +5 more
TL;DR: The present review summarizes various modern SELEX techniques used in this field, and of several currently identified aptamers against viral particles and unicellular organisms, and their applications.
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Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (A). Mechanisms of interaction.
Maksim Ionov,Joanna Lazniewska,Volha Dzmitruk,Inessa Halets,Svetlana Loznikova,D. S. Novopashina,Evgeny K. Apartsin,Olga A. Krasheninina,Alya G. Venyaminova,Katarzyna Milowska,Olga Nowacka,Rafael Gomez-Ramirez,Francisco Javier de la Mata,Jean-Pierre Majoral,Dzmitry Shcharbin,Maria Bryszewska +15 more
TL;DR: The results indicate that siRNAs form complexes with all the dendrimers tested and that Oligoribonucleotide duplexes can be released from dendriplexes after heparin treatment and the structure of siRNA is maintained in the case of PAMAM or carbosilane d endrimers.
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Multivalent Aptamers: Versatile Tools for Diagnostic and Therapeutic Applications
TL;DR: The present review summarizes approaches to the design of multivalent aptamers, various examples of multifunctional constructs and the prospects of employing them as components of biosensors, probes for affinity capture, tools for cell research and potential therapeutic candidates.