A
Alzheimer’s Disease Neuroimaging Initiative
Researcher at Indiana University
Publications - 84
Citations - 3267
Alzheimer’s Disease Neuroimaging Initiative is an academic researcher from Indiana University. The author has contributed to research in topics: Dementia & Alzheimer's Disease Neuroimaging Initiative. The author has an hindex of 24, co-authored 79 publications receiving 2236 citations. Previous affiliations of Alzheimer’s Disease Neuroimaging Initiative include Ludwig Maximilian University of Munich & Lund University.
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Journal ArticleDOI
Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease
TL;DR: Plasma NFL is associated with AD diagnosis and with cognitive, biochemical, and imaging hallmarks of the disease and implies a potential usefulness for plasma NFL as a noninvasive biomarker in AD.
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BrainAGE in Mild Cognitive Impaired Patients: Predicting the Conversion to Alzheimer’s Disease
Christian Gaser,Katja Franke,Stefan Klöppel,Nikolaos Koutsouleris,Heinrich Sauer,Alzheimer’s Disease Neuroimaging Initiative +5 more
TL;DR: A novel magnetic resonance imaging (MRI)-based biomarker that predicts the individual progression of mild cognitive impairment to AD on the basis of pathological brain aging patterns is presented and can be exploited as a tool for screening as well as for monitoring treatment options.
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Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults
TL;DR: The use of anticholinergic medication was associated with increased brain atrophy and dysfunction and clinical decline, and use of AC medication among older adults should likely be discouraged if alternative therapies are available.
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Predicting Progression from Mild Cognitive Impairment to Alzheimer's Dementia Using Clinical, MRI, and Plasma Biomarkers via Probabilistic Pattern Classification.
Igor O. Korolev,Igor O. Korolev,Laura L. Symonds,Andrea Bozoki,Alzheimer’s Disease Neuroimaging Initiative +4 more
TL;DR: The model utilizes widely available, cost-effective, non-invasive markers and can be used to improve patient selection in clinical trials and identify high-risk MCI patients for early treatment.
Journal ArticleDOI
APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern.
Shannon L. Risacher,Sungeun Kim,Kwangsik Nho,Tatiana Foroud,Li Shen,Ronald C. Petersen,Clifford R. Jack,Laurel A. Beckett,Paul S. Aisen,Robert A. Koeppe,William J. Jagust,Leslie M. Shaw,John Q. Trojanowski,Michael W. Weiner,Michael W. Weiner,Andrew J. Saykin,Alzheimer’s Disease Neuroimaging Initiative +16 more
TL;DR: In this article, the effect of APOE carrier status on Alzheimer's disease imaging and cerebrospinal fluid (CSF) biomarkers in cognitively normal older adults with significant memory concerns (SMC) was assessed.