K
Kwangsik Nho
Researcher at Indiana University
Publications - 289
Citations - 12016
Kwangsik Nho is an academic researcher from Indiana University. The author has contributed to research in topics: Medicine & Genome-wide association study. The author has an hindex of 44, co-authored 227 publications receiving 8453 citations. Previous affiliations of Kwangsik Nho include Indiana University – Purdue University Indianapolis & Regenstrief Institute.
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Journal ArticleDOI
Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
Yasser Iturria-Medina,Roberto C. Sotero,Paule-Joanne Toussaint,José María Mateos-Pérez,Alan C. Evans,Michael W. Weiner,Paul S. Aisen,Ronald C. Petersen,Clifford R. Jack,William J. Jagust,John Q. Trojanowki,Arthur W. Toga,Laurel A. Beckett,Robert C. Green,Andrew J. Saykin,John C. Morris,Leslie M. Shaw,Zaven S. Khachaturian,Greg Sorensen,Lew Kuller,Marc Raichle,Steven M. Paul,Peter Davies,Howard Fillit,Franz Hefti,Davie Holtzman,M. Marcel Mesulam,William Z. Potter,Peter J. Snyder,Adam Schwartz,T. J. Montine,Ronald G. Thomas,Michael C. Donohue,Sarah Walter,Devon Gessert,Tamie Sather,Gus Jiminez,Danielle J Harvey,Matt A. Bernstein,Nick C. Fox,Paul M. Thompson,Norbert Schuff,Bret J. Borowski,Jeff Gunter,M. L. Senjem,Prashanthi Vemuri,David T.W. Jones,Kejal Kantarci,Chad Ward,Robert A. Koeppe,Norm Foster,Eric M. Reiman,Kewei Chen,Chet Mathis,Susan M. Landau,Nigel J. Cairns,Erin Householder,Lisa Taylor-Reinwald,Virginia M.-Y. Lee,Magdalena Korecka,Michal J. Figurski,Karen Crawford,Scott C. Neu,Tatiana Foroud,Steven G. Potkin,Li Shen,Kelley Faber,Sungeun Kim,Kwangsik Nho,Leon J. Thal,Neil Buckholtz,M.S. Albert,Richard Frank,John K. Hsiao,Jeffrey Kaye,Joseph F. Quinn,Betty Lind,Raina Carter,Sara Dolen,Lon S. Schneider,Sonia Pawluczyk,Mauricio Beccera,Liberty Teodoro,Bryan M. Spann,James B. Brewer,Helen Vanderswag,Adam S. Fleisher,Judith L. Heidebrink,Joanne L. Lord,Sara S. Mason,Colleen S. Albers,David S. Knopman,Kris Johnson,Rachelle S. Doody,Javier Villanueva-Meyer,Munir Chowdhury,Susan Rountree,Mimi Dang,Yaakov Stern,Lawrence S. Honig,Karen L. Bell,Beau M. Ances,Maria Carroll,Sue Leon,Mark A. Mintun,Stacy Schneider,Angela Oliver,Daniel C. Marson,Randall Griffith,David Glenn Clark,David S. Geldmacher,John C. Brockington,Erik D. Roberson,Hillel Grossman,Effie M. Mitsis,Leyla de Toledo-Morrell,Raj C. Shah,Ranjan Duara,Daniel Varon,Maria T. Greig,Peggy Roberts,Marilyn S. Albert,Chiadi U. Onyike,Daniel D'Agostino,Stephanie Kielb,James E. Galvin,Brittany Cerbone,Christina A. Michel,Henry Rusinek,Mony J. de Leon,Lidia Glodzik,Susan De Santi,P. Murali Doraiswamy,Jeffrey R. Petrella,Terence Z. Wong,Steven E. Arnold,Jason Karlawish,David A. Wolk,Charles D. Smith,Greg Jicha,Peter A. Hardy,Partha Sinha,Elizabeth Oates,Gary R. Conrad,Oscar L. Lopez,MaryAnn Oakley,Donna M. Simpson,Anton P. Porsteinsson,Bonnie S. Goldstein,Kim Martin,Kelly M. Makino,M. Saleem Ismail,Connie Brand,Ruth A. Mulnard,Gaby Thai,Catherine Mc-Adams-Ortiz,Kyle B. Womack,Dana Mathews,Mary Quiceno,Ramon Diaz-Arrastia,Richard V. King,Myron F. Weiner,Kristen Martin-Cook,Michael D. Devous,Allan I. Levey,James J. Lah,Janet S. Cellar,Jeffrey M. Burns,Heather Anderson,Russell H. Swerdlow,Liana G. Apostolova,Kathleen Tingus,Ellen Woo,Daniel H.S. Silverman,Po H. Lu,George Bartzokis,Neill R. Graff-Radford,Francine Parfitt,Tracy Kendall,Heather Johnson,Martin R. Farlow,Annmarie Hake,Brandy R. Matthews,Scott Herring,Cynthia Hunt,Christopher H. van Dyck,Richard E. Carson,Martha G. MacAvoy,Howard Chertkow,Howard Bergman,Chris Hosein,Sandra E. Black,Bojana Stefanovic,Curtis Caldwell,Ging-Yuek Robin Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Andrew Kertesz,John Rogers,Charles Bernick,Donna Munic,Diana R. Kerwin,M.-Marsel Mesulam,Kristine Lipowski,Chuang Kuo Wu,Nancy Johnson,Carl H. Sadowsky,Walter Martinez,Teresa Villena,Raymond Scott Turner,Kathleen Johnson,Brigid Reynolds,Reisa A. Sperling,Keith A. Johnson,Gad A. Marshall,Meghan Frey,Barton Lane,Allyson Rosen,Jared R. Tinklenberg,Marwan N. Sabbagh,Christine M. Belden,Sandra Jacobson,Sherye A. Sirrel,Neil W. Kowall,Ronald J. Killiany,Andrew E. Budson,Alexander Norbash,Patricia Lynn Johnson,Joanne S. Allard,Alan J. Lerner,Paula Ogrocki,Leon Hudson,Evan Fletcher,Owen Carmichael,John M Olichney,Charles DeCarli,Smita Kittur,Michael Borrie,T. Y. Lee,Rob Bartha,Sterling C. Johnson,Sanjay Asthana,Cynthia M. Carlsson,Steven Potkin,Adrian Preda,Dana Nguyen,Pierre N. Tariot,Stephanie Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas W. Scharre,Maria Kataki,Anahita Adeli,Earl A. Zimmerman,Dzintra Celmins,Alice D. Brown,Godfrey D. Pearlson,Karen Blank,Karen E. Anderson,Robert B. Santulli,Tamar J. Kitzmiller,Eben S. Schwartz,Kaycee M. Sink,Jeff D. Williamson,Pradeep Garg,Franklin Watkins,Brian R. Ott,Henry W. Querfurth,Geoffrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard J. Rosen,Bruce L. Miller,Jacobo Mintzer,Kenneth M. Spicer,David Bachman,Elizabether Finger,Stephen H. Pasternak,Irina Rachinsky,Dick J. Drost,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Susan K. Schultz,Laura L. Boles Ponto,Hyungsub Shim,Karen Elizabeth Smith,Norman R. Relkin,Gloria Chaing,Lisa Raudin,Amanda Smith,Kristin Fargher,Balebail Ashok Raj,Thomas C. Neylan,Jordan Grafman,Melissa Davis,Rosemary H Morrison,Jacqueline Hayes,Shannon Finley,Karl E. Friedl,Debra A. Fleischman,Konstantinos Arfanakis,Olga James,Dino Massoglia,J. Jay Fruehling,Sandra Harding,Elaine R. Peskind,Eric C. Petrie,Gail Li,Jerome A. Yesavage,Joy L. Taylor,Ansgar J. Furst +314 more
TL;DR: Imaging results suggest that intra-brain vascular dysregulation is an early pathological event during disease development, suggesting early memory deficit associated with the primary disease factors.
Journal ArticleDOI
Common genetic variants influence human subcortical brain structures.
Derrek P. Hibar,Jason L. Stein,Jason L. Stein,Miguel E. Rentería,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Roberto Toro,Katharina Wittfeld,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Manon Bernard,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Andrew A. Brown,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil Lee,Phil Lee,Loes M. Olde Loohuis,Michelle Luciano,Christine Macare,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Shannon L. Risacher,Roberto Roiz-Santiañez,Emma J. Rose,Alireza Salami,Alireza Salami,Philipp G. Sämann,Lianne Schmaal,Andrew J. Schork,Jean Shin,Lachlan T. Strike,Lachlan T. Strike,Alexander Teumer,Marjolein M.J. van Donkelaar,Kristel R. van Eijk,Raymond K. Walters,Raymond K. Walters,Lars T. Westlye,Christopher D. Whelan,Anderson M. Winkler,Anderson M. Winkler,Marcel P. Zwiers,Saud Alhusaini,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Stefan Ehrlich,Marina Hakobjan,Cecilie B. Hartberg,Unn K. Haukvik,Angelien Heister,D. Hoehn,Dalia Kasperaviciute,Dalia Kasperaviciute,David C. Liewald,Lorna M. Lopez,Remco R. R. Makkinje,Mar Matarin,Marlies Naber,D. Reese McKay,Margaret Needham,Allison C. Nugent,Benno Pütz,Natalie A. Royle,Li Shen,Emma Sprooten,Emma Sprooten,Daniah Trabzuni,Daniah Trabzuni,Saskia S. L. van der Marel,Kimm J. E. van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,Laura Almasy,David Ames,David Ames,Sampath Arepalli,Amelia A. Assareh,Mark E. Bastin,Henry Brodaty,Kazima B. Bulayeva,Melanie A. Carless,Sven Cichon,Sven Cichon,Aiden Corvin,Joanne E. Curran,Michael Czisch,Greig I. de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D. Dyer,Thomas D. Dyer,Susanne Erk,Iryna O. Fedko,Luigi Ferrucci,Tatiana Foroud,Peter T. Fox,Peter T. Fox,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,Harald H H Göring,Robert C. Green,Sebastian Guelfi,Narelle K. Hansell,Catharina A. Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Pieter J. Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Ryota Kanai,Maria Keil,Jack W. Kent,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Xinmin Liu,Xinmin Liu,Dan L. Longo,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W. Montgomery,Jeanette C. Mostert,Thomas W. Mühleisen,Mike A. Nalls,Thomas E. Nichols,Thomas E. Nichols,Lars Nilsson,Markus M. Nöthen,Kazutaka Ohi,Rene L. Olvera,Rocío Pérez-Iglesias,G. Bruce Pike,Steven G. Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D. Rosen,Dan Rujescu,Knut Schnell,Peter R. Schofield,Peter R. Schofield,Colin Smith,Vidar M. Steen,Jessika E. Sussmann,Anbupalam Thalamuthu,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Jessica A. Turner,Maria C. Valdés Hernández,Dennis van 't Ent,Marcel P. van der Brug,Nic J.A. van der Wee,Marie-José van Tol,Dick J. Veltman,Thomas H. Wassink,Eric Westman,Ronald H. Zielke,Alan B. Zonderman,David G. Ashbrook,Reinmar Hager,Lu Lu,Lu Lu,Francis J. McMahon,Derek W. Morris,Derek W. Morris,Robert W. Williams,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Wiepke Cahn,Vince D. Calhoun,Vince D. Calhoun,Gianpiero L. Cavalleri,Benedicto Crespo-Facorro,Anders M. Dale,Gareth E. Davies,Norman Delanty,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Thomas Espeseth,Randy L. Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Wolfgang Hoffmann,Norbert Hosten,René S. Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W.J.H. Penninx,Joshua L. Roffman,Sanjay M. Sisodiya,Jordan W. Smoller,Jordan W. Smoller,Hans van Bokhoven,Neeltje E.M. van Haren,Henry Völzke,Henrik Walter,Michael W. Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ingrid Agartz,Ole A. Andreassen,John Blangero,John Blangero,Dorret I. Boomsma,Rachel M. Brouwer,Dara M. Cannon,Dara M. Cannon,Mark R. Cookson,Eco J. C. de Geus,Ian J. Deary,Gary Donohoe,Gary Donohoe,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Clyde Francks,Clyde Francks,David C. Glahn,Hans J. Grabe,Oliver Gruber,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E. Hulshoff Pol,Erik G. Jönsson,Erik G. Jönsson,Iwona Kłoszewska,Simon Lovestone,Simon Lovestone,Venkata S. Mattay,Patrizia Mecocci,Colm McDonald,Andrew M. McIntosh,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Andrew Simmons,Andrew B. Singleton,Hilkka Soininen,Joanna M. Wardlaw,Michael E. Weale,Daniel R. Weinberger,Hieab H.H. Adams,Lenore J. Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L. Satizabal,Claudia L. Satizabal,James T. Becker,Lisa R. Yanek,Sven J. van der Lee,Maritza Ebling,Bruce Fischl,Bruce Fischl,W. T. Longstreth,Douglas N. Greve,Helena Schmidt,Paul A. Nyquist,Louis N. Vinke,Cornelia M. van Duijn,Luting Xue,Bernard Mazoyer,Joshua C. Bis,Vilmundur Gudnason,Sudha Seshadri,Sudha Seshadri,M. Arfan Ikram,Nicholas G. Martin,Margaret J. Wright,Margaret J. Wright,Gunter Schumann,Barbara Franke,Barbara Franke,Paul M. Thompson,Sarah E. Medland +344 more
TL;DR: In this paper, the authors conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magnetic resonance images of 30,717 individuals from 50 cohorts.
Journal ArticleDOI
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Paul M. Thompson,Jason L. Stein,Sarah E. Medland,Derrek P. Hibar,Alejandro Arias Vasquez,Miguel E. Rentería,Roberto Toro,Neda Jahanshad,Gunter Schumann,Barbara Franke,Margaret J. Wright,Nicholas G. Martin,Ingrid Agartz,Ingrid Agartz,Martin Alda,Saud Alhusaini,Saud Alhusaini,Laura Almasy,Jorge R. C. Almeida,Jorge R. C. Almeida,Jorge R. C. Almeida,Kathryn I. Alpert,Nancy C. Andreasen,Ole A. Andreassen,Liana G. Apostolova,Katja Appel,Nicola J. Armstrong,Benjamin S. Aribisala,Mark E. Bastin,Michael Bauer,Carrie E. Bearden,Ørjan Bergmann,Elisabeth B. Binder,John Blangero,HJ Bockholt,Erlend Bøen,Catherine Bois,Dorret I. Boomsma,Tom Booth,Ian Bowman,Janita Bralten,Rachel M. Brouwer,Han G. Brunner,David G. Brohawn,Randy L. Buckner,Jan K. Buitelaar,Kazima B. Bulayeva,Juan R. Bustillo,Vince D. Calhoun,Vince D. Calhoun,Dara M. Cannon,Rita M. Cantor,Melanie A. Carless,Xavier Caseras,Gianpiero L. Cavalleri,M. Mallar Chakravarty,Kiki D. Chang,Christopher R.K. Ching,Andrea Christoforou,Andrea Christoforou,Sven Cichon,Sven Cichon,Vincent P. Clark,Patricia J. Conrod,Patricia J. Conrod,Giovanni Coppola,Benedicto Crespo-Facorro,Joanne E. Curran,Michael Czisch,Ian J. Deary,Eco J. C. de Geus,Anouk den Braber,G. Delvecchio,Chantal Depondt,Lieuwe de Haan,Lieuwe de Haan,Greig I. de Zubicaray,Danai Dima,Rali Dimitrova,Srdjan Djurovic,Hong-Wei Dong,Gary Donohoe,Gary Donohoe,Ravindranath Duggirala,Thomas D. Dyer,Stefan Ehrlich,Stefan Ehrlich,Carl Johan Ekman,Torbjørn Elvsåshagen,Louise Emsell,Susanne Erk,Thomas Espeseth,Jesen Fagerness,Scott C. Fears,Iryna O. Fedko,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Tatiana Foroud,Peter T. Fox,Clyde Francks,Clyde Francks,Sophia Frangou,Eva Maria Frey,Thomas Frodl,Thomas Frodl,Vincent Frouin,Hugh Garavan,Sudheer Giddaluru,David C. Glahn,Beata R. Godlewska,Rita Z. Goldstein,Randy L. Gollub,Hans J. Grabe,Oliver Grimm,Oliver Gruber,Tulio Guadalupe,Raquel E. Gur,Ruben C. Gur,Ruben C. Gur,Harald H H Göring,Saskia P. Hagenaars,Tomas Hajek,Geoffrey B. Hall,Jeremy Hall,Jeremy Hall,John Hardy,Catharina A. Hartman,Johanna Hass,Sean N. Hatton,Unn K. Haukvik,K Hegenscheid,Andreas Heinz,Ian B. Hickie,Beng-Choon Ho,D. Hoehn,Pieter J. Hoekstra,Marisa O. Hollinshead,Avram J. Holmes,Georg Homuth,Martine Hoogman,L. Elliot Hong,Norbert Hosten,Jouke-Jan Hottenga,Hilleke E. Hulshoff Pol,Kristy S. Hwang,Clifford R. Jack,Mark Jenkinson,Caroline Johnston,Caroline Johnston,Erik G. Jönsson,René S. Kahn,Dalia Kasperaviciute,Sinead Kelly,Sungeun Kim,Peter Kochunov,Laura Koenders,Laura Koenders,Bernd Krämer,John B.J. Kwok,John B.J. Kwok,Jim Lagopoulos,Gonzalo Laje,Mikael Landén,Mikael Landén,Bennett A. Landman,John Lauriello,Stephen M. Lawrie,Phil Lee,Phil Lee,Stephanie Le Hellard,Stephanie Le Hellard,Herve Lemaitre,Cassandra D. Leonardo,Chiang shan Li,Benny Liberg,David C. Liewald,Xinmin Liu,Xinmin Liu,Lorna M. Lopez,Eva Loth,Anbarasu Lourdusamy,Michelle Luciano,Fabio Macciardi,Fabio Macciardi,Marise W. J. Machielsen,Marise W. J. Machielsen,Glenda MacQueen,Ulrik Fredrik Malt,René C.W. Mandl,Dara S. Manoach,Jean-Luc Martinot,Mar Matarin,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Morten Mattingsdal,Andreas Meyer-Lindenberg,Colm McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Yuri Milaneschi,Yuri Milaneschi,Sebastian Mohnke,Grant W. Montgomery,Derek W. Morris,Eric K. Moses,Eric K. Moses,Bryon A. Mueller,Susana Muñoz Maniega,Thomas W. Mühleisen,Bertram Müller-Myhsok,Benson Mwangi,Matthias Nauck,Kwangsik Nho,Thomas E. Nichols,Lars-Göran Nilsson,Lars-Göran Nilsson,Allison C. Nugent,Lars Nyberg,Rene L. Olvera,Jaap Oosterlaan,Roel A. Ophoff,Roel A. Ophoff,Massimo Pandolfo,Melina Papalampropoulou-Tsiridou,Martina Papmeyer,Tomáš Paus,Zdenka Pausova,Godfrey D. Pearlson,Godfrey D. Pearlson,Brenda W.J.H. Penninx,Charles P. Peterson,Andrea Pfennig,Mary L. Phillips,G. Bruce Pike,Jean-Baptiste Poline,Steven G. Potkin,Benno Pütz,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Jerod M. Rasmussen,Marcella Rietschel,Mark Rijpkema,Shannon L. Risacher,Joshua L. Roffman,Roberto Roiz-Santiañez,Nina Romanczuk-Seiferth,Emma J. Rose,Natalie A. Royle,Dan Rujescu,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Alireza Salami,Alireza Salami,Theodore D. Satterthwaite,Jonathan Savitz,Jonathan Savitz,Andrew J. Saykin,Cathy Scanlon,Lianne Schmaal,Hugo G. Schnack,Andrew J. Schork,S. Charles Schulz,Remmelt R. Schür,Larry J. Seidman,Li Shen,Jody M. Shoemaker,Andrew Simmons,Andrew Simmons,Sanjay M. Sisodiya,Colin Smith,Jordan W. Smoller,Jordan W. Smoller,Jair C. Soares,Scott R. Sponheim,Scott R. Sponheim,Emma Sprooten,John M. Starr,Vidar M. Steen,Vidar M. Steen,Stephen M. Strakowski,Lachlan T. Strike,Jessika E. Sussmann,Philipp G. Sämann,Alexander Teumer,Arthur W. Toga,Diana Tordesillas-Gutiérrez,Daniah Trabzuni,Daniah Trabzuni,Sarah Trost,Jessica A. Turner,Jessica A. Turner,Martijn P. van den Heuvel,Nic J.A. van der Wee,Kristel R. van Eijk,Theo G.M. van Erp,Neeltje E.M. van Haren,Dennis van 't Ent,Marie-José van Tol,Maria C. Valdés Hernández,Dick J. Veltman,Amelia Versace,Henry Völzke,Robert Walker,Henrik Walter,Henrik Walter,Lei Wang,Joanna M. Wardlaw,Michael E. Weale,Michael W. Weiner,Wei Wen,Lars T. Westlye,Heather C. Whalley,Christopher D. Whelan,Tonya White,Anderson M. Winkler,Anderson M. Winkler,Katharina Wittfeld,Girma Woldehawariat,Christiane Wolf,David Zilles,Marcel P. Zwiers,Anbupalam Thalamuthu,Peter R. Schofield,Peter R. Schofield,Nelson B. Freimer,Natalia Lawrence,Wayne C. Drevets +332 more
TL;DR: The ENIGMA Consortium has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected.
Journal ArticleDOI
Identification of common variants associated with human hippocampal and intracranial volumes
Jason L. Stein,Sarah E. Medland,Sarah E. Medland,Alejandro Arias Vasquez,Alejandro Arias Vasquez,Derrek P. Hibar,Rudy E Senstad,Anderson M. Winkler,Anderson M. Winkler,Roberto Toro,Roberto Toro,Katja Appel,Katja Appel,Richard Barteček,Ørjan Bergmann,Manon Bernard,Andrew A. Brown,Dara M. Cannon,M. Mallar Chakravarty,Andrea Christoforou,Andrea Christoforou,Martin Domin,Oliver Grimm,Marisa O. Hollinshead,Marisa O. Hollinshead,Avram J. Holmes,Georg Homuth,Jouke-Jan Hottenga,Camilla Langan,Lorna M. Lopez,Narelle K. Hansell,Kristy S. Hwang,Sungeun Kim,Gonzalo Laje,Phil Lee,Xinmin Liu,Xinmin Liu,Eva Loth,Anbarasu Lourdusamy,Morten Mattingsdal,Sebastian Mohnke,Susana Muñoz Maniega,Kwangsik Nho,Kwangsik Nho,Allison C. Nugent,Carol O'Brien,Martina Papmeyer,Benno Pütz,Adaikalavan Ramasamy,Jerod M. Rasmussen,Mark Rijpkema,Mark Rijpkema,Shannon L. Risacher,J. Cooper Roddey,Emma J. Rose,Mina Ryten,Li Shen,Emma Sprooten,Eric Strengman,Alexander Teumer,Daniah Trabzuni,Jessica A. Turner,Kristel R. van Eijk,Theo G.M. van Erp,Marie-José van Tol,Marie-José van Tol,Marie-José van Tol,Katharina Wittfeld,Christiane Wolf,Saskia Woudstra,André Aleman,Saud Alhusaini,Laura Almasy,Elisabeth B. Binder,David G. Brohawn,Rita M. Cantor,Melanie A. Carless,Aiden Corvin,Michael Czisch,Joanne E. Curran,Gail Davies,Marcio Almeida,Norman Delanty,Norman Delanty,Chantal Depondt,Ravi Duggirala,Thomas D. Dyer,Susanne Erk,Jesen Fagerness,Peter T. Fox,Nelson B. Freimer,Michael Gill,Harald H H Göring,Donald J. Hagler,D. Hoehn,Florian Holsboer,Martine Hoogman,Norbert Hosten,Neda Jahanshad,Matthew P. Johnson,Dalia Kasperaviciute,Jack W. Kent,Peter Kochunov,Peter Kochunov,Jack L. Lancaster,Stephen M. Lawrie,David C. Liewald,René C.W. Mandl,Mar Matarin,Manuel Mattheisen,Eva M. Meisenzahl,Ingrid Melle,Ingrid Melle,Eric K. Moses,Thomas W. Mühleisen,Matthias Nauck,Markus M. Nöthen,Rene L. Olvera,Massimo Pandolfo,G. Bruce Pike,Ralf Puls,Ivar Reinvang,Miguel E. Rentería,Miguel E. Rentería,Marcella Rietschel,Joshua L. Roffman,Natalie A. Royle,Dan Rujescu,Jonathan Savitz,Jonathan Savitz,Hugo G. Schnack,Knut Schnell,Nina Y. Seiferth,Colin Smith,Vidar M. Steen,Vidar M. Steen,Maria del C. Valdés Hernández,Martijn P. van den Heuvel,Nic J.A. van der Wee,Nic J.A. van der Wee,Neeltje E.M. van Haren,Joris A. Veltman,Henry Völzke,Robert Walker,Lars T. Westlye,Christopher D. Whelan,Ingrid Agartz,Dorret I. Boomsma,Gianpiero L. Cavalleri,Anders M. Dale,Anders M. Dale,Srdjan Djurovic,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Peter Hagoort,Peter Hagoort,Peter Hagoort,Jeremy Hall,Andreas Heinz,Clifford R. Jack,Tatiana Foroud,Stephanie Le Hellard,Stephanie Le Hellard,Fabio Macciardi,Grant W. Montgomery,Jean-Baptiste Poline,David J. Porteous,Sanjay M. Sisodiya,John M. Starr,Jessika E. Sussmann,Arthur W. Toga,Dick J. Veltman,Henrik Walter,Michael W. Weiner,Joshua C. Bis,M. Arfan Ikram,Albert V. Smith,Vilmundur Gudnason,Christophe Tzourio,Christophe Tzourio,Meike W. Vernooij,Lenore J. Launer,Charles DeCarli,Sudha Seshadri,Ole A. Andreassen,Ole A. Andreassen,Liana G. Apostolova,Mark E. Bastin,John Blangero,Han G. Brunner,Randy L. Buckner,Sven Cichon,Giovanni Coppola,Giovanni Coppola,Greig I. de Zubicaray,Ian J. Deary,Gary Donohoe,Eco J. C. de Geus,Thomas Espeseth,Thomas Espeseth,Guillén Fernández,Guillén Fernández,Guillén Fernández,David C. Glahn,David C. Glahn,Hans J. Grabe,Hans J. Grabe,John Hardy,Hilleke E. Hulshoff Pol,Mark Jenkinson,René S. Kahn,Colm McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,Andreas Meyer-Lindenberg,Derek W. Morris,Bertram Müller-Myhsok,Thomas E. Nichols,Thomas E. Nichols,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Brenda W.J.H. Penninx,Steven G. Potkin,Philipp G. Sämann,Andrew J. Saykin,Gunter Schumann,Jordan W. Smoller,Joanna M. Wardlaw,Michael E. Weale,Nicholas G. Martin,Barbara Franke,Barbara Franke,Margaret J. Wright,Paul M. Thompson +237 more
TL;DR: In this article, the authors report genome-wide association meta-analyses and replication for mean bilateral hippocampal, total brain and intracranial volumes from a large multinational consortium.
Journal ArticleDOI
The genetic architecture of the human cerebral cortex
Katrina L. Grasby,Neda Jahanshad,Jodie N. Painter,Lucía Colodro-Conde,Janita Bralten,Derrek P. Hibar,Penelope A. Lind,Fabrizio Pizzagalli,Christopher R.K. Ching,Mary Agnes McMahon,Natalia Shatokhina,Leo Charles Peek Zsembik,Sophia I. Thomopoulos,Alyssa H. Zhu,Lachlan T. Strike,Ingrid Agartz,Saud Alhusaini,Marcio Almeida,Dag Alnæs,Inge K Amlien,Micael Andersson,Tyler Ard,Nicola J. Armstrong,Allison E. Ashley-Koch,Joshua R. Atkins,Manon Bernard,Rachel M. Brouwer,Elizabeth E.L. Buimer,Robin Bülow,Christian Bürger,Dara M. Cannon,M. Mallar Chakravarty,Qiang Chen,Joshua W. Cheung,Baptiste Couvy-Duchesne,Anders M. Dale,Shareefa Dalvie,Tânia Kawasaki de Araujo,Greig I. de Zubicaray,Sonja M C de Zwarte,Anouk den Braber,Nhat Trung Doan,Katharina Dohm,Stefan Ehrlich,Hannah-Ruth Engelbrecht,Susanne Erk,Chun Chieh Fan,Iryna O. Fedko,Sonya Foley,Judith M. Ford,Masaki Fukunaga,Melanie E. Garrett,Tian Ge,Sudheer Giddaluru,Aaron L. Goldman,Melissa J. Green,Nynke A. Groenewold,Dominik Grotegerd,Tiril P. Gurholt,Boris A. Gutman,Narelle K. Hansell,Mathew A. Harris,Marc B. Harrison,Courtney C. Haswell,Michael A. Hauser,Stefan Herms,Dirk J. Heslenfeld,New Fei Ho,D. Hoehn,Per Hoffmann,Laurena Holleran,Martine Hoogman,Jouke-Jan Hottenga,Masashi Ikeda,Deborah Janowitz,Iris E. Jansen,Tianye Jia,Christiane Jockwitz,Ryota Kanai,Sherif Karama,Dalia Kasperaviciute,Tobias Kaufmann,Sinead Kelly,Masataka Kikuchi,Marieke Klein,Michael Knapp,Annchen R. Knodt,Bernd Kramer,Max Lam,Thomas M. Lancaster,Phil Lee,Tristram A. Lett,Lindsay B. Lewis,Iscia Lopes-Cendes,Michelle Luciano,Fabio Macciardi,Andre F. Marquand,Samuel R. Mathias,Tracy R. Melzer,Yuri Milaneschi,Nazanin Mirza-Schreiber,José C. V. Moreira,Thomas W. Mühleisen,Bertram Müller-Myhsok,Pablo Najt,Soichiro Nakahara,Kwangsik Nho,Loes M. Olde Loohuis,Dimitri Papadopoulos Orfanos,John F. Pearson,Toni L. Pitcher,Benno Pütz,Yann Quidé,Anjanibhargavi Ragothaman,Faisal Rashid,William R. Reay,Ronny Redlich,Céline S. Reinbold,Jonathan Repple,Geneviève Richard,Brandalyn C. Riedel,Shannon L. Risacher,Cristiane S. Rocha,Nina Roth Mota,Lauren E. Salminen,Arvin Saremi,Andrew J. Saykin,Fenja Schlag,Lianne Schmaal,Peter R. Schofield,Rodrigo Secolin,Chin Yang Shapland,Li Shen,Jean Shin,Elena Shumskaya,Ida E Sønderby,Emma Sprooten,Katherine E. Tansey,Alexander Teumer,Anbupalam Thalamuthu,Diana Tordesillas-Gutiérrez,Jessica A. Turner,Anne Uhlmann,Costanza L. Vallerga,Dennis van der Meer,Marjolein M. J. Van Donkelaar,Liza van Eijk,Theo G.M. van Erp,Neeltje E.M. van Haren,Daan van Rooij,Marie-José van Tol,Jan H. Veldink,Ellen Verhoef,Esther Walton,Mingyuan Wang,Yunpeng Wang,Joanna M. Wardlaw,Wei Wen,Lars T. Westlye,Christopher D. Whelan,Stephanie H. Witt,Katharina Wittfeld,Christiane Wolf,Thomas Wolfers,Jing Qin Wu,Clarissa L. Yasuda,Dario Zaremba,Zuo Zhang,Marcel P. Zwiers,Eric Artiges,Amelia A. Assareh,Rosa Ayesa-Arriola,Aysenil Belger,Christine L. Brandt,Gregory G. Brown,Sven Cichon,Joanne E. Curran,Gareth E. Davies,Franziska Degenhardt,Michelle F. Dennis,Bruno Dietsche,Srdjan Djurovic,Colin P. Doherty,Ryan Espiritu,Daniel Garijo,Yolanda Gil,Penny A. Gowland,Robert C. Green,Alexander N. Häusler,Walter Heindel,Beng-Choon Ho,Wolfgang Hoffmann,Florian Holsboer,Georg Homuth,Norbert Hosten,Clifford R. Jack,MiHyun Jang,Andreas Jansen,Nathan A. Kimbrel,Knut K. Kolskår,Sanne Koops,Axel Krug,Kelvin O. Lim,Jurjen J. Luykx,Daniel H. Mathalon,Karen A. Mather,Venkata S. Mattay,Sarah Matthews,Jaqueline Mayoral Van Son,Sarah McEwen,Ingrid Melle,Derek W. Morris,Bryon A. Mueller,Matthias Nauck,Jan Egil Nordvik,Markus M. Nöthen,Daniel S. O'Leary,Nils Opel,Marie-Laure Paillère Martinot,G. Bruce Pike,Adrian Preda,Erin Burke Quinlan,Paul E. Rasser,Varun Ratnakar,Simone Reppermund,Vidar M. Steen,Paul A. Tooney,Fábio R. Torres,Dick J. Veltman,James T. Voyvodic,Robert Whelan,Tonya White,Hidenaga Yamamori,Hieab H.H. Adams,Joshua C. Bis,Stéphanie Debette,Charles DeCarli,Myriam Fornage,Vilmundur Gudnason,Edith Hofer,M. Arfan Ikram,Lenore J. Launer,William T. Longstreth,Oscar L. Lopez,Bernard Mazoyer,Thomas H. Mosley,Gennady V. Roshchupkin,Claudia L. Satizabal,Reinhold Schmidt,Sudha Seshadri,Qiong Yang,Marina K. M. Alvim,David Ames,Tim J. Anderson,Ole A. Andreassen,Alejandro Arias-Vasquez,Mark E. Bastin,Bernhard T. Baune,Jean C. Beckham,John Blangero,Dorret I. Boomsma,Henry Brodaty,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Juan R. Bustillo,Wiepke Cahn,Murray J. Cairns,Vince D. Calhoun,Vaughan J. Carr,Xavier Caseras,Svenja Caspers,Gianpiero L. Cavalleri,Fernando Cendes,Aiden Corvin,Benedicto Crespo-Facorro,John C. Dalrymple-Alford,Udo Dannlowski,Eco J. C. de Geus,Ian J. Deary,Norman Delanty,Chantal Depondt,Sylvane Desrivières,Gary Donohoe,Thomas Espeseth,Guillén Fernández,Simon E. Fisher,Herta Flor,Andreas J. Forstner,Clyde Francks,Barbara Franke,David C. Glahn,Randy L. Gollub,Hans J. Grabe,Oliver Gruber,Asta Håberg,Ahmad R. Hariri,Catharina A. Hartman,Ryota Hashimoto,Andreas Heinz,Frans Henskens,Manon H.J. Hillegers,Pieter J. Hoekstra,Avram J. Holmes,L. Elliot Hong,William D. Hopkins,Hilleke E. Hulshoff Pol,Terry L. Jernigan,Erik G. Jönsson,René S. Kahn,Martin A. Kennedy,Tilo Kircher,Peter Kochunov,John B.J. Kwok,Stephanie Le Hellard,Carmel M. Loughland,Nicholas G. Martin,Jean-Luc Martinot,Colm McDonald,Katie L. McMahon,Andreas Meyer-Lindenberg,Patricia T. Michie,Rajendra A. Morey,Bryan J. Mowry,Lars Nyberg,Jaap Oosterlaan,Roel A. Ophoff,Christos Pantelis,Tomáš Paus,Zdenka Pausova,Brenda W.J.H. Penninx,Tinca J. C. Polderman,Danielle Posthuma,Marcella Rietschel,Joshua L. Roffman,Laura M. Rowland,Perminder S. Sachdev,Philipp G. Sämann,Ulrich Schall,Gunter Schumann,Rodney J. Scott,Kang Sim,Sanjay M. Sisodiya,Jordan W. Smoller,Iris E. C. Sommer,Beate St Pourcain,Dan J. Stein,Arthur W. Toga,Julian N. Trollor,Nic J.A. van der Wee,Dennis van 't Ent,Henry Völzke,Henrik Walter,Bernd Weber,Daniel R. Weinberger,Margaret J. Wright,Juan Zhou,Jason L. Stein,Paul M. Thompson,Sarah E. Medland +359 more
TL;DR: Results support the radial unit hypothesis that different developmental mechanisms promote surface area expansion and increases in thickness and find evidence that brain structure is a key phenotype along the causal pathway that leads from genetic variation to differences in general cognitive function.