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Amnon Bar-Shir
Researcher at Weizmann Institute of Science
Publications - 65
Citations - 2136
Amnon Bar-Shir is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Medicine & Reporter gene. The author has an hindex of 27, co-authored 55 publications receiving 1780 citations. Previous affiliations of Amnon Bar-Shir include Tel Aviv University & Johns Hopkins University.
Papers
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Journal ArticleDOI
Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis
Alexandre S. Basso,Dan Frenkel,Dan Frenkel,Francisco J. Quintana,Frederico Azevedo da Costa-Pinto,Sanja Petrovic-Stojkovic,Lindsay Puckett,Alon Monsonego,Amnon Bar-Shir,Yoni Engel,Michael Gozin,Howard L. Weiner +11 more
TL;DR: The data demonstrate the neuroprotective effect of treatment with a fullerene compound combined with a NMDA receptor antagonist, which may be useful in the treatment of progressive MS and other neurodegenerative diseases.
Journal ArticleDOI
Variable delay multi-pulse train for fast chemical exchange saturation transfer and relayed-nuclear overhauser enhancement MRI.
Jiadi Xu,Jiadi Xu,Nirbhay N. Yadav,Nirbhay N. Yadav,Amnon Bar-Shir,Craig K. Jones,Craig K. Jones,Kannie W. Y. Chan,Kannie W. Y. Chan,Jiangyang Zhang,Piotr Walczak,Michael T. McMahon,Michael T. McMahon,Peter C.M. van Zijl,Peter C.M. van Zijl +14 more
TL;DR: A new technique, variable delay multi‐pulse CEST (VDMP‐CEST), is proposed to eliminate the need for recording full Z‐spectra and performing asymmetry analysis to obtain CEST contrast.
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Monitoring enzyme activity using a diamagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent.
Guanshu Liu,Yajie Liang,Amnon Bar-Shir,Kannie W. Y. Chan,Chulani Galpoththawela,Segun M Bernard,Terence A. Tse,Nirbhay N. Yadav,Piotr Walczak,Michael T. McMahon,Jeff W.M. Bulte,Peter C.M. van Zijl,Assaf A. Gilad +12 more
TL;DR: The findings suggest that metabolism of two substrates of the enzyme, cytosine and 5-fluorocytosine, can be detected using saturation pulses targeted specifically to protons at +2 ppm and +2.4 ppm (with respect to water), respectively.
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Transforming Thymidine into a Magnetic Resonance Imaging Probe for Monitoring Gene Expression
Amnon Bar-Shir,Guanshu Liu,Yajie Liang,Nirbhay N. Yadav,Nirbhay N. Yadav,Michael T. McMahon,Piotr Walczak,Sridhar Nimmagadda,Martin G. Pomper,Keri A. Tallman,Marc M. Greenberg,Peter C.M. van Zijl,Jeff W.M. Bulte,Assaf A. Gilad +13 more
TL;DR: 5-methyl-5,6-dihydrothymidine is identified as the optimal probe and its feasibility for in vivo imaging of HSV1-TK is demonstrated and this new approach can be generalized for designing specific probes for the in vivo Imaging of a variety of proteins and enzymes.
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Advances in using MRI probes and sensors for in vivo cell tracking as applied to regenerative medicine.
Amit K. Srivastava,Deepak K. Kadayakkara,Amnon Bar-Shir,Assaf A. Gilad,Michael T. McMahon,Jeff W.M. Bulte +5 more
TL;DR: Extraordinary efforts have recently been made to improve cellular MRI as applied to regenerative medicine, by developing more advanced contrast agents for use as probes and sensors, and of their functioning, applications and limitations.