A
Amr A. Waly
Researcher at German University in Cairo
Publications - 6
Citations - 53
Amr A. Waly is an academic researcher from German University in Cairo. The author has contributed to research in topics: microRNA & Gene. The author has an hindex of 4, co-authored 6 publications receiving 40 citations.
Papers
More filters
Journal ArticleDOI
Transcriptional activation of the IGF-II/IGF-1R axis and inhibition of IGFBP-3 by miR-155 in hepatocellular carcinoma.
TL;DR: Quantification of the expression of miR-155 demonstrated that it is upregulated in HCC, resulting in increased HCC cell carcinogenicity and may be a therapeutic target in H CC.
Journal ArticleDOI
Competing endogenous RNA network crosstalk reveals novel molecular markers in colorectal cancer.
Nehal Samir,Marwa Matboli,Hanaa El-Tayeb,Ahmed El‐Tawdi,Mohmed K. Hassan,Amr A. Waly,Hesham A. E. EL‐Akkad,Mohamed G. Ramadan,Tarek N. Al‐Belkini,Sherif F. El-Khamisy,Farid El-Asmar +10 more
TL;DR: The results revealed that the three RNAs‐based biomarker network, long non‐coding intergenic RNA‐[lncRNA RP11‐909B2.1], Homo sapiens microRNA‐595 [hsa‐mi RNA‐595], and L3MBTL1 mRNA), had high sensitivity and specificity for discriminating CRC from healthy controls and also from benign colorectal neoplasm.
Journal ArticleDOI
Methylation in MIRLET7A3 Gene Induces the Expression of IGF-II and Its mRNA Binding Proteins IGF2BP-2 and 3 in Hepatocellular Carcinoma
Amr A. Waly,Nada El-Ekiaby,R.A. Assal,Mohamed M. Abdelrahman,Karim Hosny,Hend M. El Tayebi,Gamal Esmat,Kai Breuhahn,Ahmed Ihab Abdelaziz +8 more
TL;DR: This study suggests that DNA hypermethylation leads to epigenetic repression of miR-let-7a in HCC cells, which induces the oncogenic IGF-signaling pathway.
Book ChapterDOI
Role of Protein Linked DNA Breaks in Cancer.
TL;DR: The role of topoisomerases induced PDBs, identification and signaling, repair, role in transcription, and the role of P DBs in cancer are discussed with a special focus on prostate cancer.
Journal ArticleDOI
Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer
Mohamed K. Hassan,Mohamed K. Hassan,Amr A. Waly,Waheba Elsayed,Sarah Keshk,Walaa R. Allam,Sherif F. El-Khamisy,Sherif F. El-Khamisy +7 more
TL;DR: The role of microRNAs (miRNAs) in cancer chemoresistance had been supported by many evidences as mentioned in this paper, however, their role in ovarian cancer resistance to paclitaxel (PTX) is unclear.