A
Amy Smith
Researcher at National Institutes of Health
Publications - 8
Citations - 1071
Amy Smith is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Schizophrenia & Psychosis. The author has an hindex of 8, co-authored 8 publications receiving 1060 citations. Previous affiliations of Amy Smith include University of Maryland, Baltimore.
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Journal ArticleDOI
Childhood-onset schizophrenia: A double-blind clozapine-haloperidol comparison
Sanjiv Kumra,Jean A. Frazier,Leslie K. Jacobsen,Kathleen McKenna,Charles T. Gordon,Marge C. Lenane,Susan D. Hamburger,Amy Smith,Kathleen E. Albus,Javad Alaghband-Rad,Judith L. Rapoport +10 more
TL;DR: In this article, the efficacy and adverse effects of clozapine and haloperidol were compared for children and adolescents with early-onset schizophrenia in a 6-week double-blind parallel comparison.
Journal ArticleDOI
Childhood-Onset Schizophrenia: Progressive Ventricular Change During Adolescence
Judith L. Rapoport,Jay N. Giedd,Sanjiv Kumra,Leslie K. Jacobsen,Amy Smith,Paul R. Lee,Jean Nelson,Susan D. Hamburger +7 more
TL;DR: The brain imaging results support other clinical data showing both early and late deviations in brain development for at least this rare subgroup of treatment-refractory, very-early-onset schizophrenic patients.
Journal ArticleDOI
Childhood-onset schizophrenia: an open-label study of olanzapine in adolescents.
Sanjiv Kumra,Leslie K. Jacobsen,Marge Lenane,Barbara I. Karp,Jean A. Frazier,Amy Smith,Jeffrey S. Bedwell,Paul H.K. Lee,C. J. Malanga,Susan D. Hamburger,Judith L. Rapoport +10 more
TL;DR: Preliminary evidence is provided for the efficacy of olanzapine for some children and adolescents with treatment-refractory childhood-onset schizophrenia, but the need for a more rigorous double-blind comparison of these two atypical antipsychotics is suggested.
Journal ArticleDOI
"Multidimensionally impaired disorder": is it a variant of very early-onset schizophrenia?
Sanjiv Kumra,Leslie K. Jacobsen,Marge C. Lenane,Theodore P. Zahn,Edythe Wiggs,Javad Alaghband-Rad,F. Xavier Castellanos,Jean A. Frazier,Kathleen McKenna,Charles T. Gordon,Amy Smith,Susan D. Hamburger,Judith L. Rapoport +12 more
TL;DR: The findings support the distinction of the multidimensionally impaired cases as separate from those with other psychiatric disorders, and there is somewhat greater evidence to suggest that this disorder belongs in the schizophrenia spectrum.
Journal ArticleDOI
Neuropsychological deficits in pediatric patients with childhood-onset schizophrenia and psychotic disorder not otherwise specified.
Sanjiv Kumra,Edythe Wiggs,Jeffrey S. Bedwell,Amy Smith,Elissa Arling,Katie Albus,Susan D. Hamburger,Kathleen McKenna,Leslie K. Jacobsen,Judith L. Rapoport,Robert F. Asarnow +10 more
TL;DR: Treatment-refractory PD-NOS and COS patients share a similar pattern of generalized cognitive deficits, including deficits in attention, learning and abstraction which are commonly observed in adult patients with schizophrenia.