J
Jean A. Frazier
Researcher at University of Massachusetts Medical School
Publications - 202
Citations - 13525
Jean A. Frazier is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Bipolar disorder & Autism. The author has an hindex of 59, co-authored 186 publications receiving 12025 citations. Previous affiliations of Jean A. Frazier include Columbia University & University of Massachusetts Amherst.
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Journal ArticleDOI
Family income, parental education and brain structure in children and adolescents
Kimberly G. Noble,Suzanne M. Houston,Natalie H. Brito,Hauke Bartsch,Eric Kan,Joshua M. Kuperman,Natacha Akshoomoff,David G. Amaral,Cinnamon S. Bloss,Ondrej Libiger,Nicholas J. Schork,Sarah S. Murray,B. J. Casey,Linda Chang,Thomas Ernst,Jean A. Frazier,Jeffrey R. Gruen,David N. Kennedy,Peter C.M. van Zijl,Stewart H. Mostofsky,Walter E. Kaufmann,Tal Kenet,Anders M. Dale,Terry L. Jernigan,Elizabeth R. Sowell +24 more
TL;DR: Investigation of relationships between socioeconomic factors and brain morphometry among a cohort of typically developing individuals suggests that income relates most strongly to brain structure among the most disadvantaged children.
Journal ArticleDOI
Anterior cingulate cortex dysfunction in attention-deficit/hyperactivity disorder revealed by fMRI and the counting stroop
George Bush,Jean A. Frazier,Scott L. Rauch,Larry J. Seidman,Larry J. Seidman,Paul J. Whalen,Michael A. Jenike,Bruce R. Rosen,Bruce R. Rosen,Joseph Biederman +9 more
TL;DR: The data support a hypothesized dysfunction of the ACcd in ADHD, which might contribute to producing core features of attention-deficit/hyperactivity disorder (ADHD), namely inattention and impulsivity.
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Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder
Jean A. Frazier,Sufen Chiu,Janis L. Breeze,Nikos Makris,Nicholas Lange,David N. Kennedy,Martha R. Herbert,Eileen K. Bent,Vamsi K. Koneru,Megan E. Dieterich,Steven M. Hodge,Scott L. Rauch,P. Ellen Grant,Bruce M. Cohen,Larry J. Seidman,Verne S. Caviness,Joseph Biederman +16 more
TL;DR: Findings support the hypothesis that the limbic system, in particular the hippocampus, may be involved in the pathophysiology of pediatric bipolar disorder.
Journal ArticleDOI
Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities.
TL;DR: To understand how the developmental effects of childhood maltreatment contribute to emotional dysregulation and psychiatric sequelae, the research evidence of associations between childhood trauma, emotional Dysregulation, and psychiatric comorbidities in children, adolescents, and adults is examined.
Journal ArticleDOI
Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) study
Linmarie Sikich,Jean A. Frazier,Jon McClellan,Robert L. Findling,Benedetto Vitiello,Louise Ritz,Denisse Ambler,Madeline Puglia,Ann E. Maloney,Emily S. Michael,Sandra De Jong,Karen Slifka,Nancy Noyes,Stefanie A. Hlastala,Leslie Pierson,Nora K. McNamara,Denise Delporto-Bedoya,Robert H. Anderson,Robert M. Hamer,Jeffrey A. Lieberman +19 more
TL;DR: The results question the nearly exclusive use of second-generation antipsychotics to treat early-onset schizophrenia and schizoaffective disorder and the safety findings related to weight gain and metabolic problems raise important public health concerns.