Ana Maria Oliveira Battastini

TL;DR: Observations indicate that apyrase can be detected as a phosphoprotein, with obvious implications in the regulation of this enzyme.

TL;DR: Results suggest that nasal administration of NE-siRNA CD73 exhibits higher antiglioma effect when compared to TMZ, however, no synergistic or additive in vivo was promoted by the therapeutic regimen employed in this study.

TL;DR: The results suggest the presence of a strong relation between these enzymes and the hormonal system, and the alterations observed are important, because these enzymes control the nucleotides/nucleosides ratio in the circulation and thus the events related to haemostasis.

TL;DR: It is suggested that eNT/CD73 protein expression controls cell migration and collagen expression in a mechanism independent of changes in nucleotide metabolism.

TL;DR: GEVs, administered before or at tumor challenge, have antiproliferative properties and reduce regulatory cells in the glioma microenvironment.