Anand Ramamurthi

TL;DR: Functional biomechanical properties of periostin null skin specimens and atrioventricular valve explant experiments provided direct evidence of the role that periastin plays in regulating the viscoelastic properties of connective tissues.

TL;DR: The role and significance of hyaluronan (HA), a glycosaminoglycan (GAG) component of connective tissues, in physiologic and pathologicalAngiogenesis, its applicability as a therapeutic to stimulate or suppress angiogenesis in situ within necrotic tissues in vivo, and the factors determining its potential utility as a pro-angiogenic stimulus that will enable tissue engineering of neo-vascularized and functional tissue constructs for clinical use are provided.

TL;DR: It is demonstrated that hylan gels are useful as substrates to induceElastin synthesis in culture to obtain structures that resemble the elastin matrix of the native aortic valve.

TL;DR: It is concluded that UV-treatment of hylans, useful to improve surface endothelialization, does not compromise their short-term hemocompatibility, vital to their use as vascular implant materials.

TL;DR: This study describes a method to measure the temporal NO-release rate from NO donor compounds utilizing a modified ultrafiltration cell and excellent agreement was observed between experimental and predicted NO concentrations.