Ananda S. Prasad

TL;DR: The studies showed that the cytokines produced by TH1 cells were particularly sensitive to zinc status, inasmuch as the production of interleukin-2 (IL-2) and interferon-gamma were decreased even though the deficiency of zinc was mild in subjects.

TL;DR: The essentiality of zinc in humans was established in 1963 and tremendous advances in both clinical and basic sciences of zinc metabolism in humans have been observed as discussed by the authors, and zinc has been very successfully used as a therapeutic modality for the management of acute diarrhea in children, Wilson's disease, common cold and for the prevention of blindness in patients with age-related dry type of macular degeneration.

TL;DR: A meta-analysis of zinc supplementation trials from nine countries in Latin America and the Caribbean, eight from North America or Europe, five from Asia and the Middle East, and three from Africa revealed a highly significant effect of zinc supplements on height and weight in children less than 13 years of age.

TL;DR: It is demonstrated that dietary restriction of zinc can affect testicular function adversely and can be corrected by proper supplementation with zinc, which is reversible and reversed after zinc supplementation in low doses.

TL;DR: It is hypothesized that zinc supplementation will improve T‐helper1 function and decrease incidence of infections in patients with SCD and tested this hypothesis in 32 SCD subjects, which resulted in an increase in lymphocyte and granulocyte zinc and an increased in interleukin‐2 production.