Showing papers in "Journal of Trace Elements in Medicine and Biology in 2014"
••
TL;DR: Lower cytotoxicity of the biogenic Se NPs on MCF-7 cell line was confirmed and data obtained from reducing power assay revealed higher electron-donating activity of SeO2 compared to SeNPs, while the obtained results showed that, at the same concentration of 200μg/mL, Se Nps and SeO 2 represented scavenging activity.
197 citations
••
TL;DR: Zinc supplementation studies in the elderly have shown decreased incidence of infections, decreased oxidative stress, and decreased generation of inflammatory cytokines.
192 citations
••
TL;DR: Increasing boron intake by consuming a diet rich in fruits, vegetables, nuts and pulses should be recognized as a reasonable dietary recommendation to enhance health and well-being.
189 citations
••
TL;DR: It was found that the iron distribution in the adult human brain is quite heterogeneous and the positive correlation between iron levels and age was most significant in the basal ganglia (caudate nucleus, putamen and globus pallidus), and globally, iron levels proved to be age-related.
152 citations
••
TL;DR: The essentiality of zinc in humans was established in 1963 and tremendous advances in both clinical and basic sciences of zinc metabolism in humans have been observed as discussed by the authors, and zinc has been very successfully used as a therapeutic modality for the management of acute diarrhea in children, Wilson's disease, common cold and for the prevention of blindness in patients with age-related dry type of macular degeneration.
125 citations
••
TL;DR: Investigation of the alterations in biochemical parameters, free radicals and enzyme activities induced by diazinon in male rat serum found selenium has beneficial effects and could be able to antagonize DZN toxicity.
122 citations
••
TL;DR: Manganese toxicity investigating science is spreading into different fields with very detailed and complex study designs and may finally lead to a suitable future human Mn-biomonitoring for being able to prevent or at least detect the early onset of manganism at the right time.
113 citations
••
TL;DR: Based on findings from both animal and human experiments, an intake of silicon of near 25mg/d would be a reasonable suggestion for an adequate intake that would assure its nutritional benefits.
92 citations
••
TL;DR: The presented trace element concentrations can serve as a fundamental basis for further brain research and allow a comparison with reference data from other studies.
82 citations
••
TL;DR: The findings suggest that the deficiency of Se may contribute to cognitive decline among aging people and the data point to the importance of the relation between Se exposure and cognitive function.
79 citations
••
TL;DR: This is the first report showing that selenite and MSA modulate epigenetic marks specifically in breast cancer cells, and reinforces the anti-breast cancer potential of selenium that is dependent on its chemical form.
••
TL;DR: The modes and forms of PGE emission as well as their impact on the environment and living organisms are discussed.
••
TL;DR: Cloud point extraction was used to simultaneously preconcentrate trace-level cadmium, nickel and zinc for determination by flame atomic absorption spectrometry (FAAS), yielding results in agreement with the certified values.
••
TL;DR: Results of the present investigation clearly showed that combination therapy with N-acetyl cysteine+Se provide maximum protection against mercury toxicity than monotherapy by preventing oxidative degradation of biological membrane from metal mediated free radical attacks.
••
TL;DR: It is suggested that strict glycemic control, decreased oxidative stress, and a lower copper concentration might prevent diabetic complications in patients with type 1 diabetes mellitus.
••
TL;DR: This review will focus on recent studies detailing the prevalence of poor vitamin and mineral status in female athletes, using iron, vitamin D, and calcium as examples and factors affecting the dietary requirement for these vitamins and minerals during physical training.
••
TL;DR: Reduced selenium levels were evident in all patient groups regardless of inflammation status, and male partners of infertile couples might gain some benefit from Selenium supplementation.
••
TL;DR: Observed effects of Cr on rodent models of insulin resistance and diabetes are best interpreted in terms of a pharmacological role for Cr, and it is suggested that Cr increases insulin sensitivity in peripheral tissues of the rodent models.
••
TL;DR: A review of epidemiological studies showing an increased oxidative stress in pregnant women with GDM and the potential relationship between OS induced by iron status and the development of GDM is highlighted.
••
TL;DR: A screening self-administered food frequency questionnaire for office might help caregiver's identify patients at risk of zinc deficiency.
••
TL;DR: Assessing the levels of trace elements in hair of male pattern androgenetic alopecia patients may be more valuable compared to serum and urine for treatment planning, as zinc and copper levels in hair were decreased significantly and body mass index was negatively correlated with hair zinc levels.
••
TL;DR: Taking together, supplementation with the probiotic L. plantarum IS-10506 and zinc for 90 days resulted in a significantly increased humoral immune response, as well as improved zinc status, in young children.
••
TL;DR: Investigation of long-term bioaccumulation and elimination of Cd, Pb, Mn, Zn and Fe by Pinna nobilis tissues after their 90 day-transplantation period indicates that the transplanted mussels are suitable bioindicators for monitoring trace metals in marine ecosystem.
••
TL;DR: Thio-DMA(V) is to date by far the most toxic human metabolite identified after arsenosugar intake and should contemporary be fully (also in vivo) toxicologically characterized, to assess risks to human health related to inorganic arsenic but especially arsenos sugar dietary intake.
••
TL;DR: A review highlights the benefits of using the MeHg drinking water exposure paradigm and outlines behavioral outcomes arising from this procedure in rodents and possible molecular mechanisms underlying behavioral impairment.
••
TL;DR: A study is designed and initiated of TM in canine osteosarcoma at the micrometastatic phase to help put these findings on a firm scientific basis.
••
TL;DR: Meta-analyses, genetic studies and a prognostic study evaluating the predictive value of Non-Cp copper in MCI conversion to full AD demonstrate the existence of this copper phenotype of AD.
••
TL;DR: It is concluded that early copper histidine for Menkes disease is safe and efficacious, with treatment outcomes influenced by the timing of intervention, and ATP7A mutation.
••
TL;DR: The high expression of IL1-β, TNF-α and Aβ in the cerebral cortex of pups may contribute to the impairment of learning and memory associated with maternal Pb exposure.
••
TL;DR: The present study shows that zinc chelation did not prevent neurodegeneration but did reduce TBI-induced progenitor cell proliferation and neurogenesis, suggesting that zinc has an essential role for modulating hippocampal Neurogenesis after TBI.