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Anastasia P. Kadina
Researcher at University of Southern California
Publications - 12
Citations - 206
Anastasia P. Kadina is an academic researcher from University of Southern California. The author has contributed to research in topics: Biology & Beta (finance). The author has an hindex of 6, co-authored 9 publications receiving 107 citations. Previous affiliations of Anastasia P. Kadina include Saint Petersburg State University.
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Journal ArticleDOI
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
Matthew T. N. Yarnall,Eleonora I. Ioannidi,Cian Schmitt-Ulms,Rohan N. Krajeski,Justin K. Lim,Lukas Villiger,Wenyuan Zhou,Kaiyi Jiang,Sofya K. Garushyants,Nathan Roberts,Liyang Zhang,Christopher A. Vakulskas,John A. Walker,Anastasia P. Kadina,Adrianna E Zepeda,Kevin Holden,Hong-Yu Ma,Jun Xie,Guangping Gao,Lander Foquet,Greg Bial,Sara K. Donnelly,Yoshinari Miyata,Daniel R. Radiloff,Jordana M. Henderson,Andrew Ujita,Omar O. Abudayyeh,Jonathan S. Gootenberg +27 more
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Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine
Shuting Sun,Katarzyna M. Błażewska,Katarzyna M. Błażewska,Anastasia P. Kadina,Boris A. Kashemirov,Xuchen Duan,James T. Triffitt,James E. Dunford,R. Graham G. Russell,Frank H. Ebetino,Anke J. Roelofs,Fraser P. Coxon,Mark W. Lundy,Charles E. McKenna +13 more
TL;DR: A bone imaging toolkit of 21 fluorescent probes with variable spectroscopic properties, bone mineral binding affinities, and antiprenylation activities has been created, including a novel linking strategy.
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Small Molecule Inhibition of SAMHD1 dNTPase by Tetramer Destabilization
Kyle J. Seamon,Erik C Hansen,Anastasia P. Kadina,Boris A. Kashemirov,Charles E. McKenna,Namandjé N. Bumpus,James T. Stivers +6 more
TL;DR: A nonsubstrate dUTP analogue with a methylene bridge connecting the α phosphate and 5′ carbon that potently inhibits SAMHD1 and pppCH2dU acts by a surprising allosteric mechanism that destabilizes active enzyme tetramer.
Journal ArticleDOI
Stereospecific Formation of a Ternary Complex of (S)‐α,β‐Fluoromethylene‐dATP with DNA Pol β
Brian T. Chamberlain,Vinod K. Batra,William A. Beard,Anastasia P. Kadina,David D. Shock,Boris A. Kashemirov,Charles E. McKenna,Myron F. Goodman,Samuel H. Wilson +8 more
TL;DR: The influence of water: crystallization of (R/S)-α,β-CHF-dATP with the preorganized pol β-DNA complex shows that (S)-β- CHF- dATP is preferentially bound to the active site with the C=F fluorine proximal to a structural water bound to Asp276.
Journal ArticleDOI
Intramolecular cycloaddition of azomethine ylides, from imines of O-acylsalicylic aldehyde and ethyl diazoacetate, to ester carbonyl – experimental and DFT computational study
Anastasia P. Kadina,Alexander F. Khlebnikov,Mikhail S. Novikov,Pedro J. Pérez,Dmitry S. Yufit +4 more
TL;DR: Intramolecular 1,3-dipolar cycloaddition of alkoxycarbonyl-substituted azomethine ylides to ester carbonyl was realized for the first time in the reaction of imines of O-acylsalicylic aldehyde with ethyl diazoacetate in the presence of Cu(tfacac)(2).