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Anatoly I. Miroshnikov

Researcher at Russian Academy of Sciences

Publications -  118
Citations -  1361

Anatoly I. Miroshnikov is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Nucleoside & Purine nucleoside phosphorylase. The author has an hindex of 19, co-authored 107 publications receiving 1235 citations. Previous affiliations of Anatoly I. Miroshnikov include Moscow State University.

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Biologically important nucleosides: modern trends in biotechnology and application☆

TL;DR: Some aspects of the functioning of enzymes of nucleic acid metabolism of interest as biocatalysts, the transglycosylation reaction using sugar modified nucleosides as donors of carbohydrate residues and heterocyclic bases as acceptors catalyzed by nucleoside phosphorylases and N -deoxyribosyltransferases, and the retrosynthesis are considered.
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A Convenient Approach to the Synthesis of Trinucleotide Phosphoramidites—Synthons for the Generation of Oligonucleotide/Peptide Libraries

TL;DR: Trinucleotide phosphoramidites that correspond to the codons of all 20 amino acids were synthesized in high yield in 5g scale and the synthons have been used for automated synthesis of oligonucleotides and corresponding libraries by a phosphite-triester approach.
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The conformation of gramicidin S and its N,N'-diacetyl derivative in solutions.

TL;DR: The data obtained provide unequivocal proof of the Hodchkin-Oughton-Schwyzer model of gramicidin S, for which φ and ψ coordinates are given.
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Overexpression of Escherichia coli genes encoding nucleoside phosphorylases in the pET/Bl21(DE3) system yields active recombinant enzymes.

TL;DR: Optimum conditions for biosynthesis of each enzyme as a soluble protein with intact biological activity were found and the crude preparations are approximately 80% pure and can be used immediately for enzymatic transglycosylation.
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Conformation of the Na+ complex of antamanide in solution.

TL;DR: A three dimensional structure of the antamanide·Na+ complex has been proposed containing four intramolecular hydrogen bonds formed by the amide CO and NH groups, which explains the efficiency and selectivity of theantamanide complexation reaction.