A
and Alastair W. Wark
Publications - 3
Citations - 701
and Alastair W. Wark is an academic researcher. The author has contributed to research in topics: Surface plasmon resonance & Exonuclease III. The author has an hindex of 3, co-authored 3 publications receiving 671 citations.
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Attomole Microarray Detection of MicroRNAs by Nanoparticle-Amplified SPR Imaging Measurements of Surface Polyadenylation Reactions
TL;DR: Multiple microRNAs (miRNAs) are detected in a microarray format using a novel approach that combines a surface enzyme reaction with nanoparticle-amplified SPR imaging (SPRI).
Journal ArticleDOI
Enzymatically amplified surface plasmon resonance imaging detection of DNA by exonuclease III digestion of DNA microarrays.
TL;DR: A novel approach utilizing the enzyme exonuclease III in conjunction with 3'-terminated DNA microarrays for the amplified detection of single-stranded DNA (ssDNA) with surface plasmon resonance (SPR) imaging based solely on hybridization adsorption without enzymatic amplification is described.
Journal ArticleDOI
Creating advanced multifunctional biosensors with surface enzymatic transformations
TL;DR: This paper summarizes the recent work on the coupling of surface enzyme chemistry and bioaffinity interactions on biopolymer microarrays for the creation of multiplexed biosensors with enhanced selectivity and sensitivity.