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Andrea Egan
Researcher at University of Barcelona
Publications - 9
Citations - 944
Andrea Egan is an academic researcher from University of Barcelona. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 9, co-authored 9 publications receiving 911 citations. Previous affiliations of Andrea Egan include National Institutes of Health.
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Journal ArticleDOI
The intolerable burden of malaria: a new look at the numbers.
Journal ArticleDOI
Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials
John J. Aponte,David Schellenberg,Andrea Egan,Alasdair Breckenridge,Ilona Carneiro,Julia A Critchley,Ina Danquah,Alexander N. O. Dodoo,Robin Kobbe,Bertrand Lell,Bertrand Lell,Jürgen May,Zul Premji,Sergi Sanz,Esperanza Sevene,Rachida Soulaymani-Becheikh,Peter Winstanley,Samuel Adjei,Sylvester D. Anemana,Daniel Chandramohan,Saadou Issifou,Saadou Issifou,Frank P. Mockenhaupt,Seth Owusu-Agyei,Brian Greenwood,Martin P. Grobusch,Martin P. Grobusch,Peter G. Kremsner,Peter G. Kremsner,Eusebio Macete,Hassan Mshinda,Robert D. Newman,Laurence Slutsker,Marcel Tanner,Pedro L. Alonso,Clara Menéndez +35 more
TL;DR: IPTi with sulfadoxine-pyrimethamine was safe and efficacious across a range of malaria transmission settings, suggesting that this intervention is a useful contribution to malaria control.
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Immunogenicity and Efficacy in Aotus Monkeys of Four Recombinant Plasmodium falciparum Vaccines in Multiple Adjuvant Formulations Based on the 19-Kilodalton C Terminus of Merozoite Surface Protein 1
Sanjai Kumar,William E. Collins,Andrea Egan,Anjali Yadava,Olivier Garraud,Michael J. Blackman,José A. Guevara Patiño,Carter L. Diggs,David C. Kaslow +8 more
TL;DR: The immunogenicity and protective efficacy of four versions of recombinant C-terminal 19-kDa epidermal growth factor-like region of the major surface protein 1 of Plasmodium falciparum was studied in Aotus monkeys and the need to continue the search for an adjuvant that is comparable to Freund's adjUvant in potency and is safe for use in humans is emphasized.
Journal ArticleDOI
Vaccine efficacy of recombinant Plasmodium falciparum merozoite surface protein 1 in malaria-naive, -exposed, and/or -rechallenged Aotus vociferans monkeys.
TL;DR: Protection against a lethal challenge infection of Plasmodium falciparum was elicited in malaria-naive Aotus vociferans monkeys by vaccination with the C terminus 19-kDa protein of the major merozoite surface protein fused to tetanus toxoid universal T-cell epitopes P30 and P2, and ELISA antibody titers correlated with protection.
Journal ArticleDOI
Aotus New World monkeys: model for studying malaria-induced anemia.
TL;DR: It is demonstrated that Aotus monkeys are a nonhuman primate model to gain insight into the pathogenesis of severe anemia in African children.