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Andrea Hugo
Researcher at University of the Witwatersrand
Publications - 12
Citations - 824
Andrea Hugo is an academic researcher from University of the Witwatersrand. The author has contributed to research in topics: Influenza vaccine & Vaccination. The author has an hindex of 8, co-authored 12 publications receiving 739 citations. Previous affiliations of Andrea Hugo include National Research Foundation of South Africa.
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Journal ArticleDOI
Influenza Vaccination of Pregnant Women and Protection of Their Infants
Abstr Act,Shabir A. Madhi,Clare L. Cutland,Locadiah Kuwanda,Adriana Weinberg,Andrea Hugo,Stephanie Jones,Peter V. Adrian,Nadia van Niekerk,Florette K. Treurnicht,Justin R. Ortiz,Marietjie Venter,Avy Violari,Kathleen M. Neuzil,Keith P. Klugman,Marta C. Nunes +15 more
TL;DR: Influenza vaccine was immunogenic in HIV-uninfected and HIV-infected pregnant women and provided partial protection against confirmed influenza in both groups of women and in infants who were not exposed to HIV.
Journal ArticleDOI
Influenza Vaccination of Pregnant Women and Protection of Their Infants
Shabir A. Madhi,Clare L. Cutland,Locadiah Kuwanda,Adriana Weinberg,Andrea Hugo,Stephanie Jones,Peter V. Adrian,Nadia van Niekerk,Florette K. Treurnicht,Justin R. Ortiz,Marietjie Venter,Avy Violari,Kathleen M. Neuzil,Eric A. F. Simões,Keith P. Klugman,Marta C. Nunes +15 more
TL;DR: In the HIV-infected women in the per-protocol immunogenicity arm, receipt of IIV3 resulted in increases in geometric mean titers of antibodies, which were significantly higher than titers in placebo recipients.
Journal ArticleDOI
Duration of Infant Protection Against Influenza Illness Conferred by Maternal Immunization: Secondary Analysis of a Randomized Clinical Trial
Marta C. Nunes,Clare L. Cutland,Stephanie Jones,Andrea Hugo,Richard Madimabe,Eric A. F. Simões,Eric A. F. Simões,Adriana Weinberg,Shabir A. Madhi,Shabir A. Madhi +9 more
TL;DR: Maternal immunization conferred protection against infection in the infants for a limited period during early life, and the lack of protection beyond 8 weeks of age correlated with a decrease in maternally derived antibodies.
Journal ArticleDOI
Kinetics of Hemagglutination-Inhibiting Antibodies Following Maternal Influenza Vaccination Among Mothers With and Those Without HIV Infection and Their Infants
Marta C. Nunes,Marta C. Nunes,Clare L. Cutland,Clare L. Cutland,Bonnie Dighero,Janie Bate,Stephanie Jones,Stephanie Jones,Andrea Hugo,Andrea Hugo,Nadia van Niekerk,Nadia van Niekerk,Locadiah Kuwanda,Locadiah Kuwanda,Alane Izu,Alane Izu,Adriana Weinberg,Shabir A. Madhi,Shabir A. Madhi,Shabir A. Madhi +19 more
TL;DR: Compared with HIV-un infected pregnant women, HIV-infected pregnant women had lower antibody responses and persistence and HIV-exposed infants had higher antibody levels at birth but similar antibody levels after 8 weeks of life.
Journal ArticleDOI
Efficacy, duration of protection, birth outcomes, and infant growth associated with influenza vaccination in pregnancy: a pooled analysis of three randomised controlled trials
Saad B. Omer,Dayna R Clark,Shabir A. Madhi,Milagritos D. Tapia,Marta C. Nunes,Clare L. Cutland,Eric A. F. Simões,Eric A. F. Simões,Eric A. F. Simões,Anushka R. Aqil,Joanne Katz,James M. Tielsch,Mark C. Steinhoff,Niteen Wairagkar,William Blackwelder,Joseph S. Bresee,Flanon Coulibaly,Boubacar Diallo,Fatoumata Diallo,Wilbur H Chen,Moussa Doumbia,Fadima Cheick Haidara,Adama Mamby Keita,Alexander Klimov,Mamoudou Kodio,Karen L. Kotloff,Myron M. Levine,Vladimir Mishcherkin,Uma Onwuchekwa,Sandra Panchalingam,Marcela Pasetti,Doh Sanogo,Samba Sow,Milagritos D. Tapia,Boubou Tamboura,Ibrahim Teguete,Sharon Tennant,Awa Traore,John Treanor,Janet A. Englund,Subarna K. Khatry,Jane Kuypers,Steven C. LeClerq,Luke C. Mullany,Laxman Shrestha,Peter V. Adrian,Andrea Hugo,Stephanie Jones,Locadiah Kuwanda,Keith P. Klugman,Kathleen M. Neuzil,Nadia van Niekerk,Justin R. Ortiz,Florette K. Treurnicht,Marietjie Venter,Avy Violari,Adriana Weinberg +56 more
TL;DR: There was no overall association between maternal vaccination and low birthweight, stillbirth, preterm birth, and small for gestational age and the vaccine was 50% (95% CI 32–63) efficacious against PCR-confirmed influenza.