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Karen L. Kotloff
Researcher at University of Maryland, Baltimore
Publications - 233
Citations - 13510
Karen L. Kotloff is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Vaccination & Pneumonia. The author has an hindex of 57, co-authored 230 publications receiving 10331 citations. Previous affiliations of Karen L. Kotloff include University of Maryland, College Park.
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Journal ArticleDOI
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study
Ting Shi,David A. McAllister,Katherine L. O'Brien,Eric A. F. Simões,Shabir A. Madhi,Bradford D. Gessner,Fernando P. Polack,Evelyn Balsells,Sozinho Acácio,Claudia Aguayo,Issifou Alassani,Asad Ali,Martin Antonio,Shally Awasthi,Juliet O. Awori,Eduardo Azziz-Baumgartner,Eduardo Azziz-Baumgartner,Henry C. Baggett,Vicky L. Baillie,Angel Balmaseda,Alfredo Barahona,Sudha Basnet,Sudha Basnet,Quique Bassat,Quique Bassat,Wilma Basualdo,Godfrey Bigogo,Louis Bont,Robert F. Breiman,W. Abdullah Brooks,W. Abdullah Brooks,Shobha Broor,Nigel Bruce,Dana Bruden,Philippe Buchy,Stuart Campbell,Phyllis Carosone-Link,Mandeep S. Chadha,James Chipeta,Monidarin Chou,Wilfrido Clara,Cheryl Cohen,Cheryl Cohen,Elizabeth de Cuellar,Duc Anh Dang,Budragchaagiin Dash-Yandag,Maria Deloria-Knoll,Mukesh Dherani,Tekchheng Eap,Bernard E. Ebruke,Marcela Echavarria,Carla Cecília de Freitas Lázaro Emediato,Rodrigo Fasce,Daniel R. Feikin,Luzhao Feng,Angela Gentile,Aubree Gordon,Doli Goswami,Doli Goswami,Sophie Goyet,Michelle J. Groome,Natasha B. Halasa,Siddhivinayak Hirve,Nusrat Homaira,Nusrat Homaira,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Jorge Jara,Imane Jroundi,Cissy B. Kartasasmita,Najwa Khuri-Bulos,Karen L. Kotloff,Anand Krishnan,Romina Libster,Romina Libster,Olga Lopez,Marilla G. Lucero,Florencia Lución,Socorro Lupisan,Debora N. Marcone,John P. McCracken,Mario Mejia,Jennifer C. Moïsi,Joel M. Montgomery,David P. Moore,Cinta Moraleda,Jocelyn Moyes,Jocelyn Moyes,Patrick K. Munywoki,Patrick K. Munywoki,Kuswandewi Mutyara,Mark P. Nicol,D. James Nokes,D. James Nokes,Pagbajabyn Nymadawa,Maria Tereza da Costa Oliveira,Histoshi Oshitani,Nitin Pandey,Gláucia Paranhos-Baccalà,Lia Neu Phillips,Valentina Picot,Mustafizur Rahman,Mala Rakoto-Andrianarivelo,Zeba A Rasmussen,Barbara Rath,Annick Robinson,Candice Romero,Graciela Russomando,Vahid Salimi,Pongpun Sawatwong,Nienke M Scheltema,Brunhilde Schweiger,J. Anthony G. Scott,J. Anthony G. Scott,Phil Seidenberg,Kunling Shen,Rosalyn J. Singleton,Rosalyn J. Singleton,Viviana Sotomayor,Tor A. Strand,Tor A. Strand,Agustinus Sutanto,Mariam Sylla,Milagritos D. Tapia,Somsak Thamthitiwat,Elizabeth Thomas,Rafal Tokarz,Claudia Turner,Marietjie Venter,Sunthareeya Waicharoen,Jianwei Wang,Wanitda Watthanaworawit,Lay-Myint Yoshida,Hongjie Yu,Heather J. Zar,Harry Campbell,Harish Nair,Harish Nair +138 more
TL;DR: In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.
Journal ArticleDOI
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016
Christopher Troeger,Brigette F. Blacker,Ibrahim A Khalil,Puja C Rao,Shujin Cao,Stephanie R. M. Zimsen,Samuel B. Albertson,Jeffery D Stanaway,Aniruddha Deshpande,Zegeye Abebe,Nelson Alvis-Guzman,Azmeraw T. Amare,Solomon Weldegebreal Asgedom,Zelalem Alamrew Anteneh,Carl Abelardo T. Antonio,Olatunde Aremu,Ephrem Tsegay Asfaw,Tesfay Mehari Atey,Suleman Atique,Euripide Frinel G Arthur Avokpaho,Ashish Awasthi,Henok Tadesse Ayele,Aleksandra Barac,Mauricio Lima Barreto,Quique Bassat,Saba Abraham Belay,Isabela M. Benseñor,Zulfiqar A Bhutta,Ali Bijani,Hailemichael Bizuneh,Carlos A Castañeda-Orjuela,Abel Fekadu Dadi,Lalit Dandona,Rakhi Dandona,Huyen Phuc Do,Manisha Dubey,Eleonora Dubljanin,Dumessa Edessa,Aman Yesuf Endries,Babak Eshrati,Tamer H. Farag,Garumma Tolu Feyissa,Kyle J Foreman,Mohammad H. Forouzanfar,Nancy Fullman,Peter W. Gething,Melkamu Dedefo Gishu,William W Godwin,Harish Chander Gugnani,Rashmi Gupta,Gessessew Bugssa Hailu,Hamid Yimam Hassen,Desalegn Tsegaw Hibstu,Olayinka Stephen Ilesanmi,Jost B. Jonas,Amaha Kahsay,Gagandeep Kang,Amir Kasaeian,Yousef Khader,Ejaz Ahmad Khan,Muhammad Ali Khan,Young-Ho Khang,Niranjan Kissoon,Sonali Kochhar,Karen L. Kotloff,Ai Koyanagi,G Anil Kumar,Hassan Magdy Abd El Razek,Reza Malekzadeh,Deborah Carvalho Malta,Suresh Mehata,Walter Mendoza,Desalegn Tadese Mengistu,Bereket Gebremichael Menota,Haftay Berhane Mezgebe,Fitsum Weldegebreal Mlashu,Srinivas Murthy,Gurudatta Naik,Cuong Tat Nguyen,Trang Huyen Nguyen,Dina Nur Anggraini Ningrum,Felix Akpojene Ogbo,Andrew T Olagunju,Deepak Paudel,James A Platts-Mills,Mostafa Qorbani,Anwar Rafay,Rajesh Kumar Rai,Saleem M Rana,Chhabi Lal Ranabhat,Davide Rasella,Sarah E Ray,Cesar Reis,Andre M. N. Renzaho,Mohammad Sadegh Rezai,George Mugambage Ruhago,Saeid Safiri,Joshua A. Salomon,Juan Sanabria,Benn Sartorius,Monika Sawhney,Sadaf G. Sepanlou,Mika Shigematsu,Mekonnen Sisay,Ranjani Somayaji,Chandrashekhar T Sreeramareddy,Bryan L. Sykes,Getachew Redae Taffere,Roman Topor-Madry,Bach Xuan Tran,Kald Beshir Tuem,Kingsley N. Ukwaja,Stein Emil Vollset,Judd L. Walson,Marcia R. Weaver,Kidu Gidey Weldegwergs,Andrea Werdecker,Abdulhalik Workicho,Muluken Azage Yenesew,Biruck Desalegn Yirsaw,Naohiro Yonemoto,Maysaa El Sayed Zaki,Theo Vos,Stephen S Lim,Mohsen Naghavi,Christopher J L Murray,Ali H. Mokdad,Simon I. Hay,Robert Reiner +128 more
TL;DR: Substantial progress has been made globally in reducing the burden of diarrhoeal diseases, driven by decreases in several primary risk factors, however, this reduction has not been equal across locations, and burden among adults older than 70 years requires attention.
Journal ArticleDOI
Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study
Katherine L. O'Brien,Henry C. Baggett,W. Abdullah Brooks,Daniel R. Feikin,Laura L. Hammitt,Melissa M. Higdon,Stephen R. C. Howie,Maria Deloria Knoll,Karen L. Kotloff,Orin S. Levine,Shabir A. Madhi,David R. Murdoch,Christine Prosperi,J. Anthony G. Scott,Qiyuan Shi,Donald M. Thea,Zhenke Wu,Scott L. Zeger,Peter V. Adrian,Pasakorn Akarasewi,Trevor P. Anderson,Martin Antonio,Juliet O. Awori,Vicky L. Baillie,Charatdao Bunthi,James Chipeta,Mohammod Jobayer Chisti,Jane Crawley,Andrea DeLuca,Amanda J. Driscoll,Bernard E. Ebruke,Hubert P. Endtz,Nicholas Fancourt,Wei Fu,Doli Goswami,Michelle J. Groome,Meredith Haddix,Lokman Hossain,Yasmin Jahan,E Wangeci Kagucia,Alice Kamau,Ruth A. Karron,Sidi Kazungu,Nana Kourouma,Locadiah Kuwanda,Geoffrey Kwenda,Mengying Li,Eunice M. Machuka,Grant A. Mackenzie,Nasreen Mahomed,Susan A. Maloney,Jessica McLellan,Joanne L. Mitchell,David P. Moore,Susan C. Morpeth,Azwifarwi Mudau,Lawrence Mwananyanda,James Mwansa,Micah Silaba Ominde,Uma Onwuchekwa,Daniel E. Park,Julia Rhodes,Pongpun Sawatwong,Phil Seidenberg,Arifin Shamsul,Eric A. F. Simões,Seydou Sissoko,Somwe Wa Somwe,Samba O. Sow,Mamadou Sylla,Boubou Tamboura,Milagritos D. Tapia,Somsak Thamthitiwat,Aliou Toure,Nora L. Watson,Khalequ Zaman,Syed M. A. Zaman +76 more
TL;DR: Estimating causes of pneumonia in young African and Asian children, using novel analytical methods applied to clinical and microbiological findings, estimated that viruses accounted for 61·4% (95% credible interval [CrI] 57·3–65·6) of causes, whereas bacteria accounted for 27·3% (23·3-31·6).
Journal ArticleDOI
Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016.
Ibrahim A Khalil,Christopher Troeger,Brigette F. Blacker,Puja C Rao,Alexandria Brown,Deborah Atherly,Thomas G Brewer,Cyril Engmann,Cyril Engmann,Eric R. Houpt,Gagandeep Kang,Karen L. Kotloff,Myron M. Levine,Stephen P. Luby,Calman A. MacLennan,William Pan,William Pan,Patricia B Pavlinac,James A Platts-Mills,Firdausi Qadri,Mark S. Riddle,Edward T. Ryan,David A Shoultz,A. Duncan Steele,Judd L. Walson,John W. Sanders,Ali H. Mokdad,Christopher J L Murray,Simon I. Hay,Simon I. Hay,Robert Reiner +30 more
TL;DR: The global burden of shigella and ETEC diarrhoea according to age, sex, geography, and year from 1990 to 2016 is analyzed to assess the health burden of bacterial diarrhoeal pathogens globally.
Journal ArticleDOI
Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition
Mihai Pop,Alan W. Walker,Joseph N. Paulson,Brianna Lindsay,Martin Antonio,M. Anowar Hossain,Joseph Oundo,Boubou Tamboura,Volker Mai,Irina Astrovskaya,Héctor Corrada Bravo,Richard Rance,Mark D. Stares,Myron M. Levine,Sandra Panchalingam,Karen L. Kotloff,Usman N. Ikumapayi,Chinelo Ebruke,Mitchell Adeyemi,Dilruba Ahmed,Firoz Ahmed,Meer T. Alam,Ruhul Amin,Sabbir Siddiqui,John B. Ochieng,Emmanuel Ouma,Jane Juma,Euince Mailu,Richard Omore,J. Glenn Morris,Robert F. Breiman,Debasish Saha,Julian Parkhill,James P. Nataro,O. Colin Stine +34 more
TL;DR: Overall genus-level microbiota composition exhibit a shift in controls from low to high levels of Prevotella and in MSD cases from high to low levels of Escherichia/Shigella in younger versus older children; however, there was significant variation among many genera by both site and age.