Andreas Stümpflen

TL;DR: Inclusion of detailed fetal echocardiography as a screening examination has a substantial effect on detection of congenital heart disease since a major proportion of prenatally detectable cases occur in a low-risk population.

TL;DR: The high prevalence of hyperhomocysteinemia in thrombosis patients together with the increased risk of recurrence warrants extended patient screening and the impact on the risk ofRecurrence of prolonged anticoagulation, supplementation of folate and vitamin B12, or both have to be investigated.

TL;DR: Balancing the risk of recurrent VTE and bleeding from oral anticoagulants, patients with factor V Leiden are not likely to benefit from oral anti-coagulant therapy extended beyond six months.

TL;DR: Hobbitosity for the G20210A mutation in the prothrombin gene is associated with a severe, albeit more benign, thrombotic diathesis compared with homozygosity for deficiencies of antithrombin, protein C, or protein S.

TL;DR: The risk of early recurrent venous thromboembolism is not higher in patients with the G20210A mutation than in those without the mutation, and long-term secondary thromboprophylaxis with oral anticoagulants in heterozygous carriers of the 20210A allele is not justified.