A
Andreia Valente
Researcher at University of Lisbon
Publications - 54
Citations - 1439
Andreia Valente is an academic researcher from University of Lisbon. The author has contributed to research in topics: Ruthenium & Chain transfer. The author has an hindex of 20, co-authored 48 publications receiving 1190 citations. Previous affiliations of Andreia Valente include university of lille & Centre national de la recherche scientifique.
Papers
More filters
Journal ArticleDOI
Syntheses of Macromolecular Ruthenium Compounds: A New Approach for the Search of Anticancer Drugs
Andreia Valente,M. Helena Garcia +1 more
TL;DR: In this scope, ruthenium chemistry is a rising field for the search of proficient metallodrugs by the use of macromolecular rUThenium complexes that can take advantage of the singularities of tumor cells.
Journal ArticleDOI
Polymer "ruthenium-cyclopentadienyl" conjugates - New emerging anti-cancer drugs.
Tiago Moreira,Tiago Moreira,Rita Francisco,Rita Francisco,Elisabeta Comsa,Sophie Duban-Deweer,Valérie Labas,Ana-Paula Teixeira-Gomes,Lucie Combes-Soia,Fernanda Marques,A. P. Alves de Matos,Audrey Favrelle,Cyril Rousseau,Philippe Zinck,Pierre Falson,M. Helena Garcia,Ana Preto,Andreia Valente +17 more
TL;DR: The results suggest that PMC3 is foreseen as a lead candidate to future studies and acting through a different mechanism of action than cisplatin, and established the potential of these Ru compounds as new metallodrugs for cancer chemotherapy.
Journal ArticleDOI
In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
Nuno Mendes,Francisco Tortosa,Andreia Valente,Fernanda Marques,A. P. Alves de Matos,Tânia S. Morais,Ana Isabel Tomaz,Fátima Gärtner,M. Helena Garcia +8 more
TL;DR: In vivo studies suggest a dual effect for this organometallic ruthenium(II)- cyclopentadienyl complexes not only by suppressing growth at the primary tumor tissue but also by inhibiting its metastatic behavior.
Journal ArticleDOI
New iron cyclopentadienyl complexes bearing different phosphane co-ligands: Structural factors vs. cytotoxicity
Adhan Pilon,Patrícia Gírio,Guilherme Nogueira,Fernando Avecilla,Harry Adams,Julia Lorenzo,M. Helena Garcia,Andreia Valente +7 more
TL;DR: In this article, a new family of piano stool iron-cyclopentadienyl compounds bearing different phosphane co-ligands has been synthesized and the results point out that the electronic features of the new compounds might be related to their cytotoxic activity.
Journal ArticleDOI
New iron(II) cyclopentadienyl derivative complexes: Synthesis and antitumor activity against human leukemia cancer cells
Andreia Valente,Ana M. C. Santos,Leonor Côrte-Real,M. Paula Robalo,M. Paula Robalo,Virtudes Moreno,Mercè Font-Bardia,Teresa Calvet,Julia Lorenzo,M. Helena Garcia +9 more
TL;DR: A new family of half sandwich compounds bearing a N-heteroaromatic ligand coordinated to the iron center by a nitrile functional group has been synthesized and fully characterized by NMR and UV-Vis spectroscopy as mentioned in this paper.