A
Andrew C. Briscoe
Researcher at Boston Children's Hospital
Publications - 8
Citations - 262
Andrew C. Briscoe is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Proteome & Glycomics. The author has an hindex of 8, co-authored 8 publications receiving 240 citations.
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Journal ArticleDOI
Optimizing sample handling for urinary proteomics.
Richard S. Lee,Flavio Monigatti,Andrew C. Briscoe,Zachary Waldon,Michael R. Freeman,Hanno Steen +5 more
TL;DR: It is demonstrated that the method of protein extraction, length of handling at room temperature, and repetitive freeze-thaw cycles do not seem to alter the urinary proteome at either the protein or peptide level in a manner that degrades information obtainable by mass spectrometry.
Journal ArticleDOI
PNGase F catalyzes de-N-glycosylation in a domestic microwave
TL;DR: An alternative strategy using a standard domestic microwave oven to perform the de-N-glycosylation of glycoproteins and a complex mixture from human plasma was employed, without any apparent adverse affects on the glycans or protein backbones.
Journal ArticleDOI
The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment
TL;DR: A simple and rapid sample preparation platform, the GlycoFilter, which allows a comprehensive characterization of N- glycans, N-glycosites, and proteins in a single workflow.
Journal ArticleDOI
One-Step Sample Concentration, Purification, and Albumin Depletion Method for Urinary Proteomics
TL;DR: A one-step sample preparation workflow that simultaneously concentrates proteins, purifies by removing salts and other low molecular weight compounds, and depletes (albumin) from urine samples is developed that can be multiplexed and compatible with a diverse range of downstream multidimensional separation technologies.
Journal ArticleDOI
Identification of novel non-invasive biomarkers of urinary chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network.
Adelle Dagher,Adam S. Curatolo,Monisha Sachdev,Alisa Stephens,Chris Mullins,J. Richard Landis,Adrie van Bokhoven,Andrew El-Hayek,John W. Froehlich,Andrew C. Briscoe,Roopali Roy,Roopali Roy,Jiang Yang,Jiang Yang,Michel A. Pontari,David Zurakowski,David Zurakowski,Richard S. Lee,Richard S. Lee,Marsha A. Moses,Marsha A. Moses +20 more
TL;DR: A series of candidate markers for urological chronic pelvic pain syndrome (UCPPS), selected based on their proposed involvement in underlying biological processes so as to provide new insights into pathophysiology and suggest targets for expanded clinical and mechanistic studies.