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Andrew Hardy
Researcher at Takeda Pharmaceutical Company
Publications - 3
Citations - 211
Andrew Hardy is an academic researcher from Takeda Pharmaceutical Company. The author has contributed to research in topics: Slug flow & Crystallization. The author has an hindex of 3, co-authored 3 publications receiving 166 citations. Previous affiliations of Andrew Hardy include Millennium Pharmaceuticals.
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Journal ArticleDOI
Continuous-Flow Tubular Crystallization in Slugs Spontaneously Induced by Hydrodynamics
Mo Jiang,Zhilong Zhu,Ernesto Jimenez,Charles D. Papageorgiou,Josh Waetzig,Andrew Hardy,Marianne Langston,Richard D. Braatz,Richard D. Braatz +8 more
TL;DR: The slug-flow crystallizer as mentioned in this paper is a continuous crystallizer with the potential to provide improved control of crystal properties, improved process reproducibility, and reduced scale-up risk.
Journal ArticleDOI
Indirect Ultrasonication in Continuous Slug-Flow Crystallization
Mo Jiang,Charles D. Papageorgiou,Josh Waetzig,Andrew Hardy,Marianne Langston,Richard D. Braatz +5 more
TL;DR: In this article, an indirect ultrasonication-assisted nucleation process is designed to vary the seed generation rate during operation independent of mass flow rate, by varying the ultrasonization power.
Journal ArticleDOI
Development and Scale-up of an Efficient Miyaura Borylation Process Using Tetrahydroxydiboron
Sing R. Gurung,Christopher Mitchell,Jie Huang,Marco Jonas,Josiah D. Strawser,Elena Daia,Andrew Hardy,Erin O’Brien,Frederick Hicks,Charles D. Papageorgiou +9 more
TL;DR: In this paper, a revised Miyaura borylation process was developed using tetrahydroxydiboron that avoids the use of bis(pinacolato) diborons and hence the need to hydrolyze the resulting boronic ester to its corresponding acid.