A
Andrew J. Spakowitz
Researcher at Stanford University
Publications - 103
Citations - 4836
Andrew J. Spakowitz is an academic researcher from Stanford University. The author has contributed to research in topics: Polymer & Chromatin. The author has an hindex of 31, co-authored 93 publications receiving 4110 citations. Previous affiliations of Andrew J. Spakowitz include SLAC National Accelerator Laboratory & California Institute of Technology.
Papers
More filters
Journal ArticleDOI
Bacterial chromosomal loci move subdiffusively through a viscoelastic cytoplasm.
TL;DR: In this paper, the authors track fluorescently labeled chromosomal loci in live bacterial cells and reveal a robust scaling of the mean square displacement (MSD) as τ(0.39).
Journal ArticleDOI
High flexibility of DNA on short length scales probed by atomic force microscopy
Paul A. Wiggins,Thijn van der Heijden,Fernando Moreno-Herrero,Andrew J. Spakowitz,Rob Phillips,Jonathan Widom,Cees Dekker,Philip C Nelson +7 more
TL;DR: This work uses high-resolution atomic force microscopy on individual DNA molecules to obtain a direct measurement of the bending energy function appropriate for scales down to 5 nm, and finds that on short length scales, spontaneous large-angle bends are many times more prevalent than predicted by the WLC model.
Journal ArticleDOI
Selective dispersion of high purity semiconducting single-walled carbon nanotubes with regioregular poly(3-alkylthiophene)s
Hang Woo Lee,Yeohoon Yoon,Steve Park,Joon Hak Oh,Joon Hak Oh,Sanghyun Hong,Luckshitha Suriyasena Liyanage,Huiliang Wang,Satoshi Morishita,Nishant Patil,Young-Jun Park,Jong-Jin Park,Andrew J. Spakowitz,Giulia Galli,Francois Gygi,Philip H.-S. Wong,Jeffrey B.-H. Tok,Jong Min Kim,Zhenan Bao +18 more
TL;DR: The application of regioregular poly(3-alkylthiophene)s (rr-P3ATs) to sort sc-SWNTs is reported, which offers a facile and a scalable route for separating sc- SWNTs and fabrication of electronic devices.
Journal ArticleDOI
Nonthermal ATP-dependent fluctuations contribute to the in vivo motion of chromosomal loci
TL;DR: It is shown here that locus dynamics in live bacteria and yeast are sensitive to metabolic activity, and ATP-dependent enzymatic activity, in addition to thermal fluctuations, contributes to the molecular agitation driving random (sub)diffusive motion in the living cell.
Journal ArticleDOI
Effect of force on mononucleosomal dynamics.
TL;DR: Using single-molecule optical-trapping techniques, the force-induced dynamic behavior of a single nucleosome core particle is examined and it is revealed that the outer DNA wrap is more sensitive to changes in the ionic environment than the inner DNA wrap.