S
Shirley S. Mihardja
Researcher at University of California, San Francisco
Publications - 18
Citations - 1423
Shirley S. Mihardja is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Embryonic stem cell & Cellular differentiation. The author has an hindex of 13, co-authored 17 publications receiving 1332 citations. Previous affiliations of Shirley S. Mihardja include University of California & University of California, Berkeley.
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Journal ArticleDOI
The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat
Jiashing Yu,Kim T. Du,Qizhi Fang,Yiping Gu,Shirley S. Mihardja,Richard E. Sievers,Joseph C. Wu,Randall J. Lee +7 more
TL;DR: Surface modification and microencapsulation techniques can be combined with cell transplantation leading to the maintenance of LV geometry, preservation of LV function, increase of angiogenesis and improvement of cell survival.
Journal ArticleDOI
DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC.
Yongli Zhang,Carolyn L. Smith,Anjanabha Saha,Stephan W. Grill,Shirley S. Mihardja,Steven B. Smith,Bradley R. Cairns,Craig L. Peterson,Carlos Bustamante,Carlos Bustamante +9 more
TL;DR: Monitoring the real-time activity of single ySWI/SNF or RSC complexes on single, stretched nucleosomal templates under tensions above 1 pN suggests a nucleosome-remodeling mechanism through intranucleosomal DNA loop formation, which may provide a molecular basis for the biological functions of remodelers.
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The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.
TL;DR: Injection of the alginate hydrogel into the infarct area of rats 5 weeks post-MI demonstrated that both modified and non-modifiedAlginate improve heart function, while LV function in the control group deteriorated.
Journal ArticleDOI
Effect of force on mononucleosomal dynamics.
TL;DR: Using single-molecule optical-trapping techniques, the force-induced dynamic behavior of a single nucleosome core particle is examined and it is revealed that the outer DNA wrap is more sensitive to changes in the ionic environment than the inner DNA wrap.
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Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease
Christian Heiss,Sarah Jahn,Melanie Taylor,Wendy May Real,Franca S. Angeli,Maelene L. Wong,Nicolas Amabile,Megha Prasad,Tienush Rassaf,Javier I. Ottaviani,Shirley S. Mihardja,Carl L. Keen,Matthew L. Springer,Andrew J. Boyle,William Grossman,Stanton A. Glantz,Hagen Schroeter,Yerem Yeghiazarians +17 more
TL;DR: Improvements in endothelial dysfunction by regular dietary intake of flavanols are associated with mobilization of functional CACs, and a mixed-effects linear regression model demonstrated a significant increase in flow-mediated vasodilation and a decrease in systolic blood pressure with increasing levels of CD34+/KDR+-CACs.