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Andrew Reiner
Researcher at Cold Spring Harbor Laboratory
Publications - 5
Citations - 3254
Andrew Reiner is an academic researcher from Cold Spring Harbor Laboratory. The author has contributed to research in topics: Gene & Copy-number variation. The author has an hindex of 4, co-authored 4 publications receiving 3188 citations.
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Journal ArticleDOI
Large-Scale Copy Number Polymorphism in the Human Genome
Jonathan Sebat,B. Lakshmi,Jennifer Troge,Joan Alexander,Janet M. Young,Pär Lundin,Susanne Månér,Hillary Massa,Megan Walker,Maoyen Chi,Nicholas Navin,Robert Lucito,John Healy,James W. Hicks,Kenny Q. Ye,Andrew Reiner,T. Conrad Gilliam,Barbara J. Trask,Nick Patterson,Anders Zetterberg,Michael Wigler +20 more
TL;DR: It is shown that large-scale copy number polymorphisms (CNPs) (about 100 kilobases and greater) contribute substantially to genomic variation between normal humans.
Journal ArticleDOI
Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation
Robert Lucito,John Healy,Joan Alexander,Andrew Reiner,Diane Esposito,Maoyen Chi,Linda Rodgers,Amy Brady,Jonathan Sebat,Jennifer Troge,Joseph West,Seth Rostan,Ken C. Q. Nguyen,Scott Powers,Kenneth Q. Ye,Adam B. Olshen,Ennapadam Venkatraman,Larry Norton,Michael Wigler +18 more
TL;DR: ROMA (representational oligonucleotide microarray analysis) will assist in the discovery of genes and markers important in cancer, and theiscovery of loci that may be important in inherited predisposition to disease.
Journal ArticleDOI
Detecting Gene Copy Number Fluctuations in Tumor Cells by Microarray Analysis of Genomic Representations
Robert Lucito,Joseph West,Andrew Reiner,Joan Alexander,Diane Esposito,Bhubaneswar Mishra,Scott Powers,Larry Norton,Michael Wigler +8 more
TL;DR: It is demonstrated that arrays of DNA probes derived from low-complexity representations can be used to detect amplifications, deletions, and polymorphic differences when hybridized to representations of genomic DNA.
Journal ArticleDOI
Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor
Javor P. Stolarov,Kenneth Chang,Andrew Reiner,Linda Rodgers,Gregory J. Hannon,Michael Wigler,Vivek Mittal +6 more
TL;DR: The inducibly expressed PTEN in the glioblastoma cell line, U87MG, lacking this gene shows the power of using a fully inducible expression system in conjunction with cDNA microarray analysis for exploring gene function.
Posted ContentDOI
Sex-specific DNA methylation in saliva from the multi-ethnic Fragile Families and Child Wellbeing Study
Andrew Reiner,Kelly M. Bakulski,Jonah Fisher,John F. Dou,Lisa Schneper,Colter Mitchell,Daniel A. Notterman,Matthew Zawistowski,Erin B. Ware +8 more
TL;DR: In this paper , the authors characterize sex-specific DNA methylation on autosomal chromosomes in saliva samples from children in the Fragile Families and Child Wellbeing Study, a multi-ethnic prospective birth cohort containing an oversampling of Black, Hispanic and low-income families.