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Andrey Bushmanov
Publications - 24
Citations - 162
Andrey Bushmanov is an academic researcher. The author has contributed to research in topics: Mesenchymal stem cell & Medicine. The author has an hindex of 6, co-authored 17 publications receiving 119 citations.
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Journal ArticleDOI
Changes in the Number of Double-Strand DNA Breaks in Chinese Hamster V79 Cells Exposed to γ-Radiation with Different Dose Rates
Konstantin V. Kotenko,Andrey Bushmanov,Ivan V. Ozerov,D.V. Guryev,Natalya A. Anchishkina,Nadezhda Smetanina,Ekaterina Arkhangelskaya,Natalya Y. Vorobyeva,Andreyan N. Osipov +8 more
TL;DR: The results show that the reduction of the radiation dose rate resulted in a significant decrease of DSBs per cell per an absorbed dose.
Journal ArticleDOI
Clonal chromosomal and genomic instability during human multipotent mesenchymal stromal cells long-term culture.
Victoria Nikitina,Astrelina Ta,Vladimir Nugis,Aleksandr Ostashkin,Tatiana Karaseva,Ekaterina Dobrovolskaya,Dariya Usupzhanova,Yulia Suchkova,Elena Lomonosova,Sergey Rodin,Vitaliy Brunchukov,Stanislav Lauk-Dubitskiy,Valentin Brumberg,Anastasia Machova,I. Kobzeva,Andrey Bushmanov,Aleksandr Samoilov +16 more
TL;DR: There is a need for rigorous genetic analyses of the clone formation in cultured MSCs before use in medicine, as the results of this study strongly suggest.
Journal ArticleDOI
Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells.
Margarita Pustovalova,Тatiana A. Astrelina,Anna Grekhova,Anna Grekhova,Natalia Vorobyeva,Anastasia Tsvetkova,Taisia Blokhina,Victoria Nikitina,Yulia Suchkova,D. Usupzhanova,V. Brunchukov,I. Kobzeva,Тatiana Karaseva,Ivan V. Ozerov,Aleksandr Samoylov,Andrey Bushmanov,Sergey V. Leonov,Sergey V. Leonov,Evgeny Izumchenko,Alex Zhavoronkov,Dmitry Klokov,Dmitry Klokov,Andreyan N. Osipov +22 more
TL;DR: The hypothesis that the low-dose IR induced residual γH2AХ foci do not play a role in delayed irradiation consequences, associated with cellular senescence in cultured MSCs is supported.
Journal ArticleDOI
Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells.
Margarita Pustovalova,Anna Grekhova,Тatiana A. Astrelina,Viktoria Nikitina,Ekaterina Dobrovolskaya,Yulia Suchkova,I. Kobzeva,Darya Usupzhanova,Natalia Vorobyeva,Aleksandr Samoylov,Andrey Bushmanov,Ivan V. Ozerov,Alex Zhavoronkov,Alex Zhavoronkov,Sergey V. Leonov,Dmitry Klokov,Andreyan N. Osipov,Andreyan N. Osipov +17 more
TL;DR: The results provide important information on selecting appropriate passage numbers exceeding which would be associated with substantial risks to a patient-recipient, both with respect to therapeutic efficiency and side-effects related to potential neoplastic transformations due to genetic instability acquired by MSCs during expansion.