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Andrey S. Klymchenko
Researcher at University of Strasbourg
Publications - 282
Citations - 13384
Andrey S. Klymchenko is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Fluorescence & Membrane. The author has an hindex of 54, co-authored 248 publications receiving 10474 citations. Previous affiliations of Andrey S. Klymchenko include Linköping University & Taras Shevchenko National University of Kyiv.
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Journal ArticleDOI
Solvatochromic and Fluorogenic Dyes as Environment-Sensitive Probes: Design and Biological Applications
TL;DR: Overall, solvatochromic and fluorogenic probes enable background-free bioimaging in wash-free conditions as well as quantitative analysis when combined with advanced microscopy, such as fluorescence lifetime (FLIM) and ratiometric imaging.
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Fluorescent Polymer Nanoparticles Based on Dyes: Seeking Brighter Tools for Bioimaging.
TL;DR: The strategies for synthesis of dye-loaded polymer NPs by emulsion polymerization and assembly of pre-formed polymers are described, and the resulting NPs now surpass the brightness of QDs by ≈10-fold for a comparable size, and have started reaching the level of the brightest conjugated polymer NPS.
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Fluorescent Probes for Lipid Rafts: From Model Membranes to Living Cells
Andrey S. Klymchenko,Rémy Kreder +1 more
TL;DR: An urgent need to develop new probes, specifically adapted for cell plasma membranes and compatible with modern fluorescence microscopy techniques to push the understanding of membrane microdomains forward is highlighted.
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Monitoring biophysical properties of lipid membranes by environment-sensitive fluorescent probes.
TL;DR: These probes are efficient for studying the microscopic analogs of viscosity, polarity, and hydration, as well as the molecular order, environment relaxation, and electrostatic potentials at the sites of their location.
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Switchable nile red-based probe for cholesterol and lipid order at the outer leaflet of biomembranes.
Oleksandr A. Kucherak,Sule Oncul,Zeinab Darwich,Dmytro A. Yushchenko,Youri Arntz,Pascal Didier,Yves Mély,Andrey S. Klymchenko +7 more
TL;DR: The attractive photophysical and switching properties of NR12S, together with its selective outer leaflet staining and sensitivity to cholesterol and lipid order, make it a new powerful tool for studying model and cell membranes.