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Angela Thomas
Researcher at Royal Hospital for Sick Children
Publications - 41
Citations - 2008
Angela Thomas is an academic researcher from Royal Hospital for Sick Children. The author has contributed to research in topics: Haemophilia & Population. The author has an hindex of 18, co-authored 41 publications receiving 1834 citations. Previous affiliations of Angela Thomas include Boston Children's Hospital.
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Journal ArticleDOI
Factor VIII Products and Inhibitor Development in Severe Hemophilia A
Samantha C. Gouw,Johanna G. van der Bom,Rolf Ljung,Carmen Escuriola,Ana Rosa Cid,Ségolène Claeyssens-Donadel,Christel Van Geet,Gili Kenet,Anne Mäkipernaa,Angelo Claudio Molinari,Wolfgang Muntean,Rainer Kobelt,George E Rivard,E. Santagostino,Angela Thomas,H. Marijke van den Berg +15 more
TL;DR: Recombinant and plasma-derived factor VIII products conferred similar risks of inhibitor development, and the content of von Willebrand factor in the products and switching among products were not associated with the risk of inhibitors development.
Journal ArticleDOI
Natural history of GATA1 mutations in Down syndrome
Momin Ahmed,Alexander Sternberg,Georgina W. Hall,Angela Thomas,Owen P. Smith,Aengus O'Marcaigh,Robert Wynn,Richard L. Stevens,Michael Addison,Derek J. King,Barbara Stewart,Brenda Gibson,Irene Roberts,Paresh Vyas +13 more
TL;DR: GATA1 mutations occur in utero in most DS TMD and AMKL, that they may occur without clinical signs of disease, and that multiple separate GATA1 mutant clones can occur in an individual are shown.
Journal ArticleDOI
Probiotics for maintenance of remission in ulcerative colitis
TL;DR: There is insufficient evidence to make conclusions about the efficacy of probiotics for maintenance of remission in UC, and a lack of well-designed RCTs in this area is needed.
Journal ArticleDOI
European principles of haemophilia care.
B. T. Colvin,Jan Astermark,Krista Fischer,Alessandro Gringeri,Riitta Lassila,W. Schramm,Angela Thomas,Jørgen Ingerslev +7 more
TL;DR: This document sets out the principles of comprehensive haemophilia care in Europe and the need for education and research programmes for all staff members is emphasized.
Journal ArticleDOI
Early factor VIII exposure and subsequent inhibitor development in children with severe haemophilia A
Elizabeth Chalmers,S. A. Brown,David Keeling,R. Liesner,M Richards,David Stirling,Angela Thomas,Vicky Vidler,Michael Williams,David Young +9 more
TL;DR: Exposure to FVIII during the neonatal period was not associated with a higher incidence of inhibitors than those treated later during the first year of life and the presence of a major molecular defect were the most important variables affecting inhibitor development.