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Anika Sadowski
Researcher at University of Erlangen-Nuremberg
Publications - 2
Citations - 768
Anika Sadowski is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Transforming growth factor & Fibrosis. The author has an hindex of 2, co-authored 2 publications receiving 655 citations.
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Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
Alfiya Akhmetshina,Katrin Palumbo,Clara Dees,Christina Bergmann,Paulius Venalis,Pawel Zerr,Angelika Horn,Trayana Kireva,Christian Beyer,Jochen Zwerina,Holm Schneider,Anika Sadowski,Marc Oliver Riener,Ormond A. MacDougald,Oliver Distler,Georg Schett,Jörg H W Distler +16 more
TL;DR: It is demonstrated that canonical Wnt signalling is necessary for TGF-β-mediated fibrosis and highlight a key role for the interaction of both pathways in the pathogenesis of fibrotic diseases.
Journal ArticleDOI
Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
Jérôme Avouac,Jérôme Avouac,Katrin Palumbo,Michal Tomcik,Pawel Zerr,Clara Dees,Angelika Horn,Britta Maurer,Alfiya Akhmetshina,Christian Beyer,Anika Sadowski,Holm Schneider,Shunichi Shiozawa,Oliver Distler,Georg Schett,Yannick Allanore,Jörg H W Distler +16 more
TL;DR: Up-regulation of c-Jun and c-Fos was detected in mouse models of SSc and in the skin and dermal fibroblasts of patients with SSc, indicating AP-1 is up-regulated in a TGFβ-dependent manner in SSc.