Anirban Siddhanta

TL;DR: The results suggest that phospholipid metabolism plays an important role in the release of nascent secretory vesicles from the TGN.

TL;DR: Using biochemical and microscopic techniques, it is demonstrated that the nuclear pool of PIP5K is modified by SUMO-1 in HEK-293 cells stably expressing PIP4K and increased during apoptosis.

TL;DR: P-PD mediated apoptotic death of both human and mouse melanoma cells in vitro is demonstrated and suggests that p-PD can be a potential less expensive candidate to be developed as a chemotherapeutic agent for melanoma.

TL;DR: In vitro serine phosphorylation of recombinant LegH by a homologous kinase caused a reduction in its oxygen consumption as determined by Clark type electrode, and molecular modeling study showed that particularly S45 is the most critical one, along with S55, however the latter with lesser impact on its molecular environment responsible for oxygen consumption.

TL;DR: Several up- and down-regulated proteins in hyperglycemic rat pancreas are revealed including the downregulation of a Pancreas specific isoform of protein disulphide isomerase a2 (Pdia2) which was validated by western blot.