A
Anna Partyka
Researcher at Jagiellonian University Medical College
Publications - 90
Citations - 1453
Anna Partyka is an academic researcher from Jagiellonian University Medical College. The author has contributed to research in topics: Receptor & Agonist. The author has an hindex of 20, co-authored 80 publications receiving 1142 citations. Previous affiliations of Anna Partyka include Centre national de la recherche scientifique & Jagiellonian University.
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Journal ArticleDOI
Antidepressant and antipsychotic activity of new quinoline- and isoquinoline- sulfonamide analogs of aripiprazole targeting serotonin 5-HT1A/5-HT2A/5-HT7 and dopamine D2/D3 receptors
Paweł Zajdel,Krzysztof Marciniec,Andrzej Maślankiewicz,Katarzyna Grychowska,Grzegorz Satała,Beata Duszyńska,Tomasz Lenda,Agata Siwek,Gabriel Nowak,Anna Partyka,Dagmara Wróbel,Magdalena Jastrzębska-Więsek,Andrzej J. Bojarski,Anna Wesołowska,Maciej Pawłowski +14 more
TL;DR: A series of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole was synthesized to explore the influence of two structural features - replacement of ether/amide moiety with sulfonamide one, and localization of a sulf onamide group in the azine moiety.
Journal ArticleDOI
Antidepressant‐like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents
Gabriel Nowak,Anna Partyka,A. Palucha,Bernadeta Szewczyk,Joanna M. Wierońska,Małgorzata Dybała,M. Metz,Tadeusz Librowski,Wolfgang Froestl,Mariusz Papp,Andrzej Pilc,Andrzej Pilc +11 more
TL;DR: In this paper, the authors investigated the antidepressant-like activity of the selective GABAB receptor antagonists CGP 36742 and CGP 51176, and a selective agonist CGP 44532 in models of depression in rats and mice.
Antidepressant-like activity of CGP 36742 and CGP 51176
G. Nowak,Anna Partyka,A. Palucha,Bernadeta Szewczyk,Joanna M. Wierońska,Małgorzata Dybała,M. Metz,T. Librowski,Wolfgang Froestl,Mariusz Papp,Andrzej Pilc +10 more
TL;DR: Investigation of the antidepressant‐like activity of the selective GABAB receptor antagonists CGP 36742 and CGP 51176 and a selective agonist CGP 44532 in models of depression in rats and mice finds limited data to support this proposition.
Journal ArticleDOI
Quinoline- and isoquinoline-sulfonamide analogs of aripiprazole: novel antipsychotic agents?
Paweł Zajdel,Anna Partyka,Krzysztof Marciniec,Andrzej J. Bojarski,Maciej Pawłowski,Anna Wesołowska +5 more
TL;DR: This review presents the state of the development of novel antipsychotic dopaminergic and non-dopaminergic agents and presents the strategic development of long-chain arylpiperazine-derived quinoline- and isoquinoline-sulfonamide displaying a multireceptor binding profile and partial D2 receptor agonism.
Journal ArticleDOI
Quinoline- and isoquinoline-sulfonamide derivatives of LCAP as potent CNS multi-receptor-5-HT1A/5-HT2A/5-HT7 and D2/D3/D4-agents: the synthesis and pharmacological evaluation.
Paweł Zajdel,Krzysztof Marciniec,Andrzej Maślankiewicz,Grzegorz Satała,Beata Duszyńska,Andrzej J. Bojarski,Anna Partyka,Magdalena Jastrzębska-Więsek,Dagmara Wróbel,Anna Wesołowska,Maciej Pawłowski +10 more
TL;DR: Two series of arylpiperazinyl-alkyl quinoline-, isoquinoline-, naphthalene-sulfonamides with flexible and semi-rigid alkylene spacer produced antidepressant-like effects in the forced swim test in mice and showed significant anxiolytic activity in the plus-maze test in rats.