A
Andrzej Maślankiewicz
Researcher at Medical University of Silesia
Publications - 40
Citations - 399
Andrzej Maślankiewicz is an academic researcher from Medical University of Silesia. The author has contributed to research in topics: Quinoline & Carbon-13 NMR. The author has an hindex of 10, co-authored 40 publications receiving 370 citations.
Papers
More filters
Journal ArticleDOI
Antidepressant and antipsychotic activity of new quinoline- and isoquinoline- sulfonamide analogs of aripiprazole targeting serotonin 5-HT1A/5-HT2A/5-HT7 and dopamine D2/D3 receptors
Paweł Zajdel,Krzysztof Marciniec,Andrzej Maślankiewicz,Katarzyna Grychowska,Grzegorz Satała,Beata Duszyńska,Tomasz Lenda,Agata Siwek,Gabriel Nowak,Anna Partyka,Dagmara Wróbel,Magdalena Jastrzębska-Więsek,Andrzej J. Bojarski,Anna Wesołowska,Maciej Pawłowski +14 more
TL;DR: A series of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole was synthesized to explore the influence of two structural features - replacement of ether/amide moiety with sulfonamide one, and localization of a sulf onamide group in the azine moiety.
Journal ArticleDOI
Quinoline- and isoquinoline-sulfonamide derivatives of LCAP as potent CNS multi-receptor-5-HT1A/5-HT2A/5-HT7 and D2/D3/D4-agents: the synthesis and pharmacological evaluation.
Paweł Zajdel,Krzysztof Marciniec,Andrzej Maślankiewicz,Grzegorz Satała,Beata Duszyńska,Andrzej J. Bojarski,Anna Partyka,Magdalena Jastrzębska-Więsek,Dagmara Wróbel,Anna Wesołowska,Maciej Pawłowski +10 more
TL;DR: Two series of arylpiperazinyl-alkyl quinoline-, isoquinoline-, naphthalene-sulfonamides with flexible and semi-rigid alkylene spacer produced antidepressant-like effects in the forced swim test in mice and showed significant anxiolytic activity in the plus-maze test in rats.
Journal ArticleDOI
Structure assignment of some 3,4′-diquinolinyl sulfides studied by Nuclear Overhauser Effects, X-ray analysis and reactions with sodium methoxide†
Stanisław Boryczka,Andrzej Maślankiewicz,Miroslaw Wyszomirski,Teresa Borowiak,Maciej Kubicki +4 more
TL;DR: In this article, 1H NMR spectral assignment and nuclear Overhauser enhancement studies of 3-methylthio)-4-quinolinyl]-4-methoxyquinoline (2) and -4(1H)-quinolinone (3) were carried out.
Journal ArticleDOI
Arene- and quinoline-sulfonamides as novel 5-HT7 receptor ligands.
Paweł Zajdel,Krzysztof Marciniec,Andrzej Maślankiewicz,Maria H. Paluchowska,Grzegorz Satała,Anna Partyka,Magdalena Jastrzębska-Więsek,Dagmara Wróbel,Anna Wesołowska,Beata Duszyńska,Andrzej J. Bojarski,Maciej Pawłowski +11 more
TL;DR: Compound 54 (N-Ethyl-N-[4-(1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinolin-2-yl]butyl]-8-quinolinesulfonamide) was identified as potent 5-HT(7) antagonist with good selectivity over 5-ht(1A), 5- HT(2A),5-HT
Journal ArticleDOI
From haloquinolines and halopyridines to quinoline- and pyridinesulfonyl chlorides and sulfonamides #
TL;DR: The action of sodium methanethiolate (in boiling DMF) towards haloazines (i.e., chloro- or bromo-pyridines and quinolines) causes sequentially halogen substituent substitution to methylthioazines (2) and then S-demethylation to azinethiolates (3A), which were: i) subjected to S-methylation, ii) oxidized to diazinyl disulfides (4) and iii) oxidatively chlorinated to azinesulfonyl