A
Anne Galinier
Researcher at Paul Sabatier University
Publications - 102
Citations - 5590
Anne Galinier is an academic researcher from Paul Sabatier University. The author has contributed to research in topics: Catabolite repression & Bacillus subtilis. The author has an hindex of 42, co-authored 95 publications receiving 5222 citations. Previous affiliations of Anne Galinier include University of Lyon & Centre national de la recherche scientifique.
Papers
More filters
Journal ArticleDOI
Diabetic β-Cells Can Achieve Self-Protection against Oxidative Stress through an Adaptive Up-Regulation of Their Antioxidant Defenses
Gregory Lacraz,Florence Figeac,Jamileh Movassat,Nadim Kassis,Josiane Coulaud,Anne Galinier,Corinne Leloup,D. Bailbé,Françoise Homo-Delarche,Bernard Portha +9 more
TL;DR: The GK/Par model illustrates the effectiveness of adaptive response to OS by β-cells to achieve self-tolerance, and shows that such a phenotype was not innate but spontaneously acquired after diabetes onset, as the result of an adaptiveresponse to the diabetic environment.
Journal ArticleDOI
Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat.
Gregory Lacraz,M.H. Giroix,Nadim Kassis,Josiane Coulaud,Anne Galinier,Christophe Noll,Mélanie Cornut,Fabien Schmidlin,Jean-Louis Paul,Nathalie Janel,Jean-Claude Irminger,Micheline Kergoat,Bernard Portha,Marc Y. Donath,Jan A. Ehses,Françoise Homo-Delarche +15 more
TL;DR: GK rat islets have increased mRNA expression of markers of early islet endothelial cell activation, possibly triggered by several metabolic factors, and also some defense mechanisms, which highlights a major endothelial-related role for IL-1 in GK islet alterations.
Journal ArticleDOI
HPr kinase/phosphorylase, a Walker motif A-containing bifunctional sensor enzyme controlling catabolite repression in Gram-positive bacteria
Sandrine Poncet,Ivan Mijakovic,Sylvie Nessler,Virginie Gueguen-Chaignon,Vincent Chaptal,Anne Galinier,Grégory Boël,Alain Mazé,Josef Deutscher +8 more
TL;DR: Biochemical and structural studies revealed that HprK/P exhibits no similarity to eukaryotic protein kinases and that it contains a Walker motif A (or P-loop) as nucleotide binding site and has a structural fold resembling that in kinases phosphorylating certain low molecular weight substrates such as nucleosides, nucleotides or oxaloacetate.
Journal ArticleDOI
Balancing mitochondrial redox signaling: a key point in metabolic regulation.
Corinne Leloup,Louis Casteilla,Audrey Carrière,Anne Galinier,Alexandre Benani,Lionel Carneiro,Luc Pénicaud +6 more
TL;DR: Recent studies that support the hypothesis that mROS are an integrated physiological signal of the metabolic status of the cell are considered, which is of paramount importance in controlling body weight and, therefore, the development of obesity and type 2 diabetes.
Journal ArticleDOI
Weight-dependent changes of immune system in adipose tissue: importance of leptin.
Sylvie Caspar-Bauguil,Béatrice Cousin,Mireille André,Maryse Nibbelink,Anne Galinier,Brigitte Périquet,Louis Casteilla,Luc Pénicaud +7 more
TL;DR: The present study suggests that adipose tissues present, according to their localization, different immunological mechanisms that might be involved in the regulation of adipose cells functions and proliferations.