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Anne-Laure Roux
Researcher at Versailles Saint-Quentin-en-Yvelines University
Publications - 46
Citations - 1951
Anne-Laure Roux is an academic researcher from Versailles Saint-Quentin-en-Yvelines University. The author has contributed to research in topics: Mycobacterium abscessus & Medicine. The author has an hindex of 18, co-authored 39 publications receiving 1620 citations. Previous affiliations of Anne-Laure Roux include French Institute of Health and Medical Research & Pasteur Institute.
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Journal ArticleDOI
Assessment of Clarithromycin Susceptibility in Strains Belonging to the Mycobacterium abscessus Group by erm(41) and rrl Sequencing
Sylvaine Bastian,Nicolas Veziris,Anne-Laure Roux,Florence Brossier,Jean-Louis Gaillard,Vincent Jarlier,Emmanuelle Cambau +6 more
TL;DR: Clarithromycin-resistant strains, including the six rrl mutants, were more often isolated in cystic fibrosis patients, but this was not significantly associated with a previous treatment.
Journal ArticleDOI
Multicenter study of prevalence of nontuberculous mycobacteria in patients with cystic fibrosis in france.
Anne-Laure Roux,Emilie Catherinot,Fabienne Ripoll,Nathalie Soismier,Edouard Macheras,Sophie Ravilly,Gil Bellis,Marie-Anne Vibet,Evelyne Le Roux,Lydie Lemonnier,Cristina Gutierrez,Véronique Vincent,Brigitte Fauroux,Martin Rottman,Didier Guillemot,Didier Guillemot,Didier Guillemot,Jean-Louis Gaillard +17 more
TL;DR: A multicenter prevalence study of nontuberculous mycobacteria involving 1,582 patients with cystic fibrosis in France found the most common NTM species and the only ones associated with fulfillment of the American Thoracic Society bacteriological criteria for NTM lung disease were Mycobacterium abscessus complex andMAC.
Journal ArticleDOI
Multilocus Sequence Analysis and rpoB Sequencing of Mycobacterium abscessus (Sensu Lato) Strains
Edouard Macheras,Anne-Laure Roux,Sylvaine Bastian,Sylvia Cardoso Leão,Moises Palaci,Valérie Sivadon-Tardy,Cristina Gutierrez,Elvira Richter,Sabine Rüsch-Gerdes,Gaby E. Pfyffer,Thomas Bodmer,Emmanuelle Cambau,Jean-Louis Gaillard,Beate Heym +13 more
TL;DR: This study strongly supports the recent proposal that M. abscessus, M. massiliense, and M. bolletii should constitute a single species and indicates there has been a horizontal transfer of rpoB sequences between these subgroups.
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Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus.
Alexandre Pawlik,Guillaume Garnier,Mickael Orgeur,Pin Tong,Amanda J. Lohan,Fabien Le Chevalier,Guillaume Sapriel,Anne-Laure Roux,Kevin M. Conlon,Nadine Honoré,Marie-Agnès Dillies,Laurence Ma,Christiane Bouchier,Jean-Yves Coppée,Jean-Louis Gaillard,Stephen V. Gordon,Brendan J. Loftus,Roland Brosch,Jean-Louis Herrmann +18 more
TL;DR: To better understand the molecular mechanisms behind the S/R alterations, S and R variants of three isogenic M. abscessus pairs are analysed using an unbiased approach involving genome and transcriptome analyses, transcriptional fusions and integrating constructs to identify clearly defined genetic lesions responsible for the loss of GPL‐production or transport.
Journal ArticleDOI
Acute respiratory failure involving an R variant of Mycobacterium abscessus
Emilie Catherinot,Anne-Laure Roux,Edouard Macheras,Dominique Hubert,Moussa Matmar,Luc Dannhoffer,Thierry Chinet,Philippe Morand,Claire Poyart,Beate Heym,Martin Rottman,Jean-Louis Gaillard,Jean-Louis Herrmann +12 more
TL;DR: The case of a cystic fibrosis patient colonized with a smooth-morphotype form of Mycobacterium abscessus who developed acute respiratory failure with the emergence of an isogenic rough (R) variant while he was recovering from peritonitis-induced shock is reported.