A
Anne-Marie Houot
Researcher at Collège de France
Publications - 15
Citations - 1490
Anne-Marie Houot is an academic researcher from Collège de France. The author has contributed to research in topics: Exon & Genetic linkage. The author has an hindex of 14, co-authored 15 publications receiving 1445 citations. Previous affiliations of Anne-Marie Houot include French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene.
TL;DR: The gene duplication suggested by the internal homology of the endothelial ACE mRNA is now confirmed by the presence of two homologous clusters of eight exons having similar sizes and codon phases at exon-intron boundaries.
Journal ArticleDOI
Multiple Promoters in the WNK1 Gene: One Controls Expression of a Kidney-Specific Kinase-Defective Isoform
Céline Delaloy,Jingyu Lu,Anne-Marie Houot,Sandra Disse-Nicodeme,Jean-Marie Gasc,Pierre Corvol,Xavier Jeunemaitre +6 more
TL;DR: Control of human WNK1 gene expression of kinase-active or -deficient isoforms is mediated predominantly through the use of multiple transcription initiation sites and tissue-specific regulatory elements.
Journal ArticleDOI
Mapping of a First Locus for Autosomal Dominant Myxomatous Mitral-Valve Prolapse to Chromosome 16p11.2-p12.1
Sandra Disse,Eric Abergel,Alain Berrebi,Anne-Marie Houot,Jean-Yves Le Heuzey,Benoit Diebold,Louis Guize,Alain Carpentier,Pierre Corvol,Xavier Jeunemaitre +9 more
TL;DR: By systematic echocardiographic screening of the first-degree relatives of 17 patients who underwent mitral-valve repair, four pedigrees showing an autosomal dominant inheritance of the trait are identified, demonstrating the genetic heterogeneity of the disease.
Journal ArticleDOI
Genetic Analysis of the β Subunit of the Epithelial Na+ Channel in Essential Hypertension
Alexandre Persu,Pascal Barbry,Frederic Bassilana,Anne-Marie Houot,Raymond Mengual,Michel Lazdunski,Pierre Corvol,Xavier Jeunemaitre +7 more
TL;DR: The present study illustrates the difficulty in establishing a relation of causality between a susceptibility gene and hypertension and does not favor a substantial role of the betaENaC gene in essential hypertension.
Journal ArticleDOI
Sib pair linkage analysis of renin gene haplotypes in human essential hypertension
TL;DR: The sib pair analysis suggests that the renin gene does not have a frequent role in the pathogenesis of essential hypertension; further more powerful linkage studies or other approaches will be needed to detect contributions at the renIn locus to the heritability of essential pulmonary hypertension.