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Anne-Sophie Charbonnier
Researcher at French Institute of Health and Medical Research
Publications - 11
Citations - 957
Anne-Sophie Charbonnier is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Dendritic cell & Chemokine. The author has an hindex of 9, co-authored 11 publications receiving 932 citations. Previous affiliations of Anne-Sophie Charbonnier include Pasteur Institute.
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Journal ArticleDOI
Peroxisome proliferator‐activated receptor γ activators affect the maturation of human monocyte‐derived dendritic cells
Philippe Gosset,Anne-Sophie Charbonnier,Philippe Delerive,Josette Fontaine,Bart Staels,Joël Pestel,André-Bernard Tonnel,François Trottein +7 more
TL;DR: The data suggest that activation of PPARγ in human DC may have an impact in the orientation of primary and secondary immune responses by favoring type 2 responses.
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Th2 polarization by Der p 1–pulsed monocyte-derived dendritic cells is due to the allergic status of the donors
Hamida Hammad,Anne-Sophie Charbonnier,Catherine Duez,Alain Jacquet,Geoffrey A. Stewart,André-Bernard Tonnel,Joël Pestel +6 more
TL;DR: DCs from house dust mite--sensitive patients, in contrast to DCs from healthy donors and from pollen- sensitive patients, exposed to Der p 1 play a pivotal role in the enhancement of the Th2 response associated with the allergic reaction developed in response to house dustmite exposure.
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Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment.
Muriel Pichavant,Anne-Sophie Charbonnier,Solenne Taront,A Brichet,Benoit Wallaert,Joël Pestel,André-Bernard Tonnel,Philippe Gosset +7 more
TL;DR: These data confirmed that BECs participate in the homeostasis of the DC network present within the bronchial epithelium through the secretion of chemokines.
Journal ArticleDOI
Activation of the D prostanoid receptor 1 regulates immune and skin allergic responses.
Veronique Angeli,Delphine Staumont,Anne-Sophie Charbonnier,Hamida Hammad,Philippe Gosset,Muriel Pichavant,Bart N. Lambrecht,Monique Capron,David Dombrowicz,François Trottein +9 more
TL;DR: Analysis of the local response indicates that BW245C treatment strongly reduces the recruitment of inflammatory cells into the dermis and disrupts the Th1/Th2 balance, probably through the increased production of the immunoregulatory cytokine IL-10, in the skin of sensitized mice.
Journal ArticleDOI
Involvement of CCL18 in Allergic Asthma
Patricia de Nadai,Anne-Sophie Charbonnier,Cécile Chenivesse,Stéphanie Sénéchal,Clément Fournier,Jules Gilet,Han Vorng,Ying Chang,Ying Chang,Philippe Gosset,Benoit Wallaert,André-Bernard Tonnel,Philippe Lassalle,Anne Tsicopoulos +13 more
TL;DR: Functionally, CCL18 preferentially attracted in vitro-polarized Th2 cells and basophils, but not eosinophils and Th1 cells, and induced basophil histamine and intracellular calcium release, and suggest that CCL 18 may play a predominant role in allergic asthma.