Anthony M. Zador

TL;DR: In this paper, the authors identify previously unrecognized spatial organization in connectivity along the anterior-posterior axis (A-P) of the piriform cortex and find that both the bulb projections to the cortex and the cortical outputs are not random, but rather form gradients along the A-P axis.

TL;DR: In this paper , the authors propose centralized brain observatories for large-scale recordings of neural activity in mice and non-human primates coupled with cloud-based data analysis and sharing.

TL;DR: In SYNseq, each neuron is labeled with a unique random nucleotide sequence—an RNA “barcode”—which is targeted to the synapse using engineered proteins and joined into a form suitable for sequencing.

TL;DR: In vivo whole cell patch methods to record the synaptic response to two-tone stimuli in the primary auditory cortex of anesthetized rats found that the amplitude of the postsynaptic potentials (PSP) evoked by the second tone varies as a function of both the frequency and intensity of the first tone.

TL;DR: It is shown in mice that DH-BB(5’SIN;TE12ORF)- packaged virus eliminates infection of cells outside the injection site, and provides evidence that ectopically labeled cells observed in previous experiments with recombinant Sindbis virus resulted from secondary infection by propagation-competent virus, rather than from inefficient retrograde spread.