Antonella Vardeu

TL;DR: GDM impairs HUVEC function via miR-101 upregulation, and EZH2 is both a transcriptional inhibitor and a target gene of mi R-101 in HUV ECs, and it contributes to some of the miR -101-induced defects of GDM-HUVECs.

TL;DR: It is suggested that CYP2C9 mediates resveratrol-induced oxidative stress leading to mitochondria impairment and EC death, and the specific cytochrome P450 (CYP) 2C9 inhibitor, sulfaphenazole, counteracted both oxidative stress and mitochondrial membrane depolarization, providing EC protection against resver atrol-elicited pro-oxidant effects.

TL;DR: Moderate high doses of coumaric acid can promote CYP2C9-mediated oxidative stress eliciting mitochondrial-dependent ECs death and may pave the way toward mechanistic insight into NA effects on cardiovascular cells.

TL;DR: It is concluded that a highly efficient GLU biosensor of minimal dimensions can be consistently and affordably constructed with relative ease and together with the possibility of cryopreservation this shall foster diffusion and exploitation ofGLU biosensors technology.

TL;DR: Plasma miR-1 is suggested as a novel potential circulating biomarker to predict early postoperative outcome and inform clinical management in pediatric heart surgery.