A
Aoife Lowery
Researcher at National University of Ireland, Galway
Publications - 180
Citations - 4409
Aoife Lowery is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 23, co-authored 129 publications receiving 3478 citations. Previous affiliations of Aoife Lowery include Beaumont Hospital & University College Hospital.
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Journal ArticleDOI
Circulating microRNAs as novel minimally invasive biomarkers for breast cancer.
TL;DR: Findings suggest that systemic miRNAs have potential use as novel breast cancer biomarkers and may prove useful in clinical management during the perioperative period.
Journal ArticleDOI
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/ neu receptor status in breast cancer
Aoife Lowery,Nicola Miller,Amanda Devaney,Roisin E McNeill,Pamela A Davoren,Christophe Lemetre,Vladimir Benes,Sabine Schmidt,Jonathon Blake,Graham Ball,Michael J. Kerin +10 more
TL;DR: This study demonstrates that ANN analysis reliably identifies biologically relevant miRNAs associated with specific breast cancer phenotypes and indicates that dysregulated miRNA expression could be a marker for poorer prognosis breast cancer, but that it could also present an attractive target for therapeutic intervention.
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Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells.
Roisin M. Dwyer,S.M. Potter-Beirne,K.A. Harrington,Aoife Lowery,E. Hennessy,James M. Murphy,Frank Barry,Timothy O'Brien,Michael J. Kerin +8 more
TL;DR: A role for tumor-secreted MCP-1 in stimulating MSC migration is highlighted and the potential of mesenchymal stem cells as tumor-targeted delivery vehicles for therapeutic agents is supported.
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Locoregional recurrence after breast cancer surgery: a systematic review by receptor phenotype.
TL;DR: Patients with triple-negative and HER2/neu-overexpressing breast tumors are at increased risk of developing LRR following BCT or mastectomy and Luminal tumors exhibit the lowest rates of LRR.
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Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer
TL;DR: This is the first study to identify reliable ECs for analysis of miRNA by RQ-PCR by examining the expression of five miRNA genes across malignant, benign and normal breast tissues.