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Armando Gómez-Puyou
Researcher at National Autonomous University of Mexico
Publications - 131
Citations - 2839
Armando Gómez-Puyou is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: ATPase & ATP hydrolysis. The author has an hindex of 29, co-authored 131 publications receiving 2716 citations. Previous affiliations of Armando Gómez-Puyou include Instituto Politécnico Nacional.
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Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense STEADY-STATE ADP FORMATION AS A REGULATORY MECHANISM OF MEMBRANE POTENTIAL AND REACTIVE OXYGEN SPECIES GENERATION IN MITOCHONDRIA
Wagner Seixas da-Silva,Armando Gómez-Puyou,Marietta Tuena de Gómez-Puyou,Rafael Moreno-Sánchez,Fernanda G. De Felice,Leopoldo de Meis,Marcus F. Oliveira,Antonio Galina +7 more
TL;DR: It is shown that the ADP produced by hexokinase activity in rat brain mitochondria (mt-hexokinase) controls both membrane potential (Δψm) and ROS generation and mitochondrial ROS generation through an ADP-recycling mechanism.
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Enzymes in Low Water Systems
TL;DR: The studies show that low water environments can be used to stabilize conformers that exhibit unsuspected catalytic properties, as well as intermediates of enzyme function and formation that in aqueous media have relatively short life-times.
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Effect of the pH of the incubation medium on glycolysis and respiration in Saccharomyces cerevisiae
TL;DR: The results presented in this communication do not support the idea that the pH of the yeast cell remains constant with variations of the pHof the incubation medium, and have important implications for the regulation of both glycolysis and respiration in yeast as a consequence of the changes of the external pH.
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Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface.
Claudia Rodríguez-Almazán,Rodrigo Arreola,David Rodriguez-Larrea,Beatriz Aguirre-López,Marietta Tuena de Gómez-Puyou,Ruy Pérez-Montfort,Miguel Costas,Armando Gómez-Puyou,Alfredo Torres-Larios +8 more
TL;DR: It is shown that the purified, recombinant mutant enzyme E104D, while exhibiting normal catalytic activity, shows impairments in the formation of active dimers and low thermostability and monomerizes under conditions in which the wild type retains its dimeric form.
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Using evolutionary changes to achieve species-specific inhibition of enzyme action — studies with triosephosphate isomerase
Armando Gómez-Puyou,Emma Saavedra-Lira,Ingeborg Becker,Rafael A. Zubillaga,Arturo Rojo-Domlnguez,Ruy Pérez-Montfort +5 more
TL;DR: Cys14 of trypanosomal TIM is a non-conserved amino acid whose alteration leads to loss of enzyme structure and function and methyl methanethiosulfonate may offer an alternative route to species-specific enzyme inhibition.