Showing papers by "Armando Santoro published in 1992"
TL;DR: Clinical results achieved at the Milan Cancer Institute in advanced Hodgkin's disease through successive randomized studies performed during the last two decades confirm the therapeutic activity of a regimen containing bleomycin and doxorubicin, and can be refined in the attempt to further decrease iatrogenic toxicity.
42 citations
24 citations
TL;DR: The use of neuroendocrine immunoperoxidase markers to predict chemotherapy response in patients with non-small cell lung cancer and a comparison between ABC and unlabelled antibody (PAP) procedures is compared.
16 citations
TL;DR: The major practical effect of this induction chemotherapy is the selection of patients with better prognosis and the possibility of perform, in some cases, easier limb salvage procedures, which seems to provide little better but not yet significant results.
13 citations
10 citations
TL;DR: The challenge in the management of Hodgkin's disease in this decade will probably be represented by an optimal use of reasonably short-term chemotherapy regimens combined with limited-field irradiation in early stages and by an accurate evaluation of the best chemotherapy regimen for advanced disease.
Abstract: Through the careful application of appropriate staging procedures and treatment modalities, at the beginning of the 1990s about 75% of patients with Hodgkin's disease can expect long-term remission or even cure. At present, radiotherapy remains the best therapeutic option for localized stages while advanced disease is cured by chemotherapy alone or chemotherapy combined with irradiation. In this decade, the challenge in the management of Hodgkin's disease will probably be represented by an optimal use of reasonably short-term chemotherapy regimens combined with limited-field irradiation in early stages and by an accurate evaluation of the best chemotherapy regimens for advanced disease. In the search for the optimal approaches to improve current therapeutic results, appropriate considerations should be given to the identification of effective treatment modalities with a minimum amount of acute and late toxicity.
5 citations