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Arnaud Friggeri
Researcher at Claude Bernard University Lyon 1
Publications - 106
Citations - 4080
Arnaud Friggeri is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Medicine & Intensive care. The author has an hindex of 24, co-authored 91 publications receiving 3235 citations. Previous affiliations of Arnaud Friggeri include University of Lyon & BioMérieux.
Papers
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Journal ArticleDOI
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
Gang Liu,Arnaud Friggeri,Yanping Yang,Jadranka Milosevic,Qiang Ding,Victor J. Thannickal,Naftali Kaminski,Edward Abraham +7 more
TL;DR: An important role for miR-21 in fibrotic lung diseases is demonstrated and a novel approach using miRNA therapeutics in treating clinically refractory fibrotics diseases, such as IPF, is suggested.
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miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses
TL;DR: A negative-feedback loop is demonstrated in which TLR stimulation induces miR-147 to prevent excessive inflammatory responses and functioned as a negative regulator of TLR-associated signaling events in murine macrophages.
Journal ArticleDOI
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.
Jaroslaw W. Zmijewski,Sami Banerjee,Hong-Beom Bae,Arnaud Friggeri,Eduardo R. Lazarowski,Edward Abraham +5 more
TL;DR: This paper showed that increased intracellular levels of reactive oxygen species can stimulate AMPK activity, even without a decrease in cellular levels of ATP. And they also showed that physiologically relevant concentrations of H2O2 can activate AMPK through oxidative modification of the AMPKα subunit.
Exposure to hydrogen peroxide induces oxidation and activation of
Jaroslaw W. Zmijewski,Sami Banerjee,Hong-Beom Bae,Arnaud Friggeri,Edward Abraham,Jaroslaw Zmijewski +5 more
TL;DR: It is demonstrated that physiologically relevant concentrations of H2O2 can activate AMPK through oxidative modification of the AMPKα subunit, and implies that AMPK activation, in addition to being a response to alterations in intracellular metabolic pathways, is directly influenced by cellular redox status.
Journal ArticleDOI
Skin antisepsis with chlorhexidine–alcohol versus povidone iodine–alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial
Olivier Mimoz,Olivier Mimoz,Jean-Christophe Lucet,Jean-Christophe Lucet,Thomas Kerforne,Julien Pascal,Bertrand Souweine,Véronique Goudet,Alain Mercat,Lila Bouadma,Lila Bouadma,Sigismond Lasocki,Serge Alfandari,Arnaud Friggeri,Florent Wallet,Nicolas Allou,Stéphane Ruckly,Dorothée Balayn,Alain Lepape,Jean-François Timsit,Jean-François Timsit +20 more
TL;DR: For skin antisepsis, chlorhexidine-alcohol provides greater protection against short-term catheter-related infections than does povidone iodine-alcohol and should be included in all bundles for prevention of intravascular catheter -related infections.