A
Arthur K. Cho
Researcher at University of California, Los Angeles
Publications - 174
Citations - 10875
Arthur K. Cho is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Metabolite & Dopamine. The author has an hindex of 49, co-authored 168 publications receiving 10185 citations. Previous affiliations of Arthur K. Cho include Oklahoma State University Center for Health Sciences.
Papers
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Journal ArticleDOI
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage.
Ning Li,Constantinos Sioutas,Arthur K. Cho,Debra A. Schmitz,Chandan Misra,Joan M. Sempf,Meiying Wang,Terry D. Oberley,John R. Froines,Andre E. Nel +9 more
TL;DR: The studies demonstrate that the increased biological potency of UFPs is related to the content of redox cycling organic chemicals and their ability to damage mitochondria.
Journal ArticleDOI
Redox activity of airborne particulate matter at different sites in the Los Angeles Basin.
Arthur K. Cho,Constantinos Sioutas,Constantinos Sioutas,Antonio H. Miguel,Yoshito Kumagai,Yoshito Kumagai,Debra A. Schmitz,Manisha Singh,Manisha Singh,Arantza Eiguren-Fernandez,John R. Froines +10 more
TL;DR: It is found that PM will catalyze the reduction of oxygen and the distribution and chemical characteristics of the redox activity of PM fractions collected in different sites in the Los Angeles Basin are examined.
Journal ArticleDOI
Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement.
Jon G Ayres,Paul J. A. Borm,Flemming R. Cassee,Vincent Castranova,Ken Donaldson,A.J. Ghio,Roy M. Harrison,Robert C. Hider,Frank J. Kelly,Ingeborg M. Kooter,Francelyne Marano,Robert L. Maynard,Ian Mudway,Andre E. Nel,Constantinos Sioutas,Steve Smith,Armelle Baeza-Squiban,Arthur K. Cho,Sean T Duggan,John R. Froines +19 more
TL;DR: In vitro test methods have an important role to play in the screening of toxicity in airborne particulate matter and nanoparticles and offer large cost advantages relative to human or animal inhalation studies and animal in vivo installation experiments.
Journal ArticleDOI
Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals
Ning Li,Jawed Alam,M. Indira Venkatesan,Arantza Eiguren-Fernandez,Debra A. Schmitz,Emma Di Stefano,Ndaisha Slaughter,Erin Killeen,Xiaorong Wang,Aaron Huang,Meiying Wang,Antonio H. Miguel,Arthur K. Cho,Constantinos Sioutas,Constantinos Sioutas,Andre E. Nel +15 more
TL;DR: This study investigates the mechanism by which redox cycling organic chemicals, prepared from DEP, induce phase II enzyme expression as a protective response and proposes that Nrf2-mediated phase II enzymes expression protects against the proinflammatory effects of particulate pollutants in the setting of allergic inflammation and asthma.
Journal ArticleDOI
The Chemical Biology of Naphthoquinones and Its Environmental Implications
TL;DR: The chemistry, biochemistry, and cellular effects of 1,2- and 1,4-naphthoquinones and their derivatives are described, which are of particular interest because of their prevalence as natural products and as environmental chemicals.