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Ashley M. Kopec

Researcher at Albany Medical College

Publications -  33
Citations -  658

Ashley M. Kopec is an academic researcher from Albany Medical College. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 12, co-authored 23 publications receiving 392 citations. Previous affiliations of Ashley M. Kopec include Duke University & Harvard University.

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Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats.

TL;DR: It is demonstrated that in male but not female rats, dopamine receptors are tagged by complement for microglial phagocytosis, thus mediating changes in social behavior, thereby demonstrating for the first time that microglia and complement-mediated immune signaling participate in adolescent brain development in a sex-specific manner.
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Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

TL;DR: An overview of the basic biology of myelin lipids and recent insights on the regulation of fatty acid metabolism and functions in myelinating cells are presented to provide a foundation for future research characterizing the role of fatty acids and lipids in myelin biology and metabolic disorders affecting the central and peripheral nervous system.
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MAPK Establishes a Molecular Context That Defines Effective Training Patterns for Long-Term Memory Formation

TL;DR: These findings provide the first demonstration of a requirement for MAPK in the intertrial interactions during memory formation and suggest that the kinetics of MAPK activation following individual experiences determines effective training intervals for LTM formation.
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Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue

TL;DR: This method is suitable for assessing gene and protein expression from a single brain sample, allowing for a more comprehensive evaluation of neural phenomena while minimizing the number of subjects.
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Neuro-Immune Mechanisms Regulating Social Behavior: Dopamine as Mediator?

TL;DR: This review synthesize literature demonstrating the bidirectional relationship between social behavior and immune signaling and highlight recent work linking social behavior, immune function, and dopaminergic signaling in adolescent neural and behavioral development.