A
Ashutosh Singh
Researcher at University of Delhi
Publications - 36
Citations - 1406
Ashutosh Singh is an academic researcher from University of Delhi. The author has contributed to research in topics: Candida auris & Medicine. The author has an hindex of 14, co-authored 27 publications receiving 858 citations. Previous affiliations of Ashutosh Singh include Banaras Hindu University & Physical Research Laboratory.
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A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009-17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance.
Anuradha Chowdhary,Anupam Prakash,Cheshta Sharma,Milena Kordalewska,Anil Kumar,Smita Sarma,Bansidhar Tarai,Ashutosh Singh,Gargi Upadhyaya,Shalini Upadhyay,Priyanka Yadav,Pradeep Kumar Singh,Vikas Khillan,Neelam Sachdeva,David S. Perlin,Jacques F. Meis +15 more
TL;DR: The antifungal susceptibility of C. auris isolates from 10 hospitals in India collected over a period of 8 years was studied, finding that 25% and 13% of isolates were MDR and multi-azole resistant, respectively.
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High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene.
Ashutosh Singh,Aradhana Masih,Ananta Khurana,Pradeep Kumar Singh,Meenakshi Gupta,Ferry Hagen,Jacques F. Meis,Anuradha Chowdhary +7 more
TL;DR: A considerably high terbinafine resistance rate of 32% was observed among 63 T. interdigitale isolates identified by sequencing of the internal transcribed spacer region, which is worrisome warranting antifungal susceptibility testing and mutation analysis for monitoring this emerging resistance.
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Limited ERG11 Mutations Identified in Isolates of Candida auris Directly Contribute to Reduced Azole Susceptibility.
Kelley R. Healey,Milena Kordalewska,Cristina Jiménez Ortigosa,Ashutosh Singh,Indira Berrio,Anuradha Chowdhary,David S. Perlin +6 more
TL;DR: Multiple Erg11 amino acid substitutions were identified in clinical isolates of Candida auris originating from India and Colombia; however, expression of alleles encoding I466M, Y501H, or other clade-defined amino acid differences yielded susceptible MICs.
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A unique multidrug-resistant clonal Trichophyton population distinct from Trichophyton mentagrophytes/Trichophyton interdigitale complex causing an ongoing alarming dermatophytosis outbreak in India: Genomic insights and resistance profile.
Ashutosh Singh,Aradhana Masih,Juan Monroy-Nieto,Pradeep Kumar Singh,Jolene Bowers,Jason Travis,Ananta Khurana,David M. Engelthaler,Jacques F. Meis,Anuradha Chowdhary +9 more
TL;DR: This study highlights difficulties in identifying isolates from the Trichophyton mentagrophytes/interdigitale clade of the genus using currently available molecular tools and highlights the potential of this organism to rapidly spread alleles that might be driving antifungal resistance among its population.
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Environmental Isolation of Candida auris from the Coastal Wetlands of Andaman Islands, India
Parth Arora,Parth Arora,Prerna Singh,Yue Wang,Anamika Yadav,Kalpana Pawar,Ashutosh Singh,G. Padmavati,Jianping Xu,Anuradha Chowdhary +9 more
TL;DR: In this article, the authors explored the virgin habitats around the very isolated Andaman Islands in the Indian Ocean for evidence of C. auris, including rocky shores, sandy beaches, tidal marshes, and mangrove swamps.