A
Ashwin N. Ananthakrishnan
Researcher at Harvard University
Publications - 529
Citations - 30046
Ashwin N. Ananthakrishnan is an academic researcher from Harvard University. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 70, co-authored 468 publications receiving 22807 citations. Previous affiliations of Ashwin N. Ananthakrishnan include Boston Children's Hospital & Indian Institute of Technology Madras.
Papers
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Journal ArticleDOI
Geographical variation and incidence of inflammatory bowel disease among US women
Hamed Khalili,Edward S. Huang,Ashwin N. Ananthakrishnan,Leslie M. Higuchi,James M. Richter,Charles S. Fuchs,Charles S. Fuchs,Andrew T. Chan,Andrew T. Chan +8 more
TL;DR: In a population of US women, increasing latitude of residence was associated with a higher incidence of Crohn's disease and UC.
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Impact of Clostridium difficile on inflammatory bowel disease
TL;DR: Both vancomycin and metronidazole appear to be effective and treatment with oral vancomYcin is preferred in those with severe disease, including those who require hospitalization, and there is a need to prospectively examine whether CDI has long-term disease-modifying consequences inThose with underlying IBD.
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Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease.
Ashwin N. Ananthakrishnan,Andrew Cagan,Vivian S. Gainer,Tianxi Cai,Su Chun Cheng,Guergana Savova,Pei Chen,Peter Szolovits,Zongqi Xia,Zongqi Xia,Philip L. De Jager,Philip L. De Jager,Stanley Y. Shaw,Susanne Churchill,Elizabeth W. Karlson,Elizabeth W. Karlson,Isaac S. Kohane,Isaac S. Kohane,Isaac S. Kohane,Robert M. Plenge,Robert M. Plenge,Shawn N. Murphy,Shawn N. Murphy,Katherine P. Liao,Katherine P. Liao +24 more
TL;DR: In this paper, the authors suggest that vitamin D may have an immunological role in Crohn's disease (CD) and ulcerative colitis (UC) and that there is a weak association between vitamin D status and disease activity but have significant limitations.
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Review article: vitamin D and inflammatory bowel diseases
TL;DR: Vitamin D is traditionally associated with bone metabolism, but the immunological effects of vitamin D have increasingly come into focus.
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A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
Melissa K. Takahashi,Xiao Tan,Aaron J. Dy,Aaron J. Dy,Dana Braff,Dana Braff,Reid T. K. Akana,Yoshikazu Furuta,Yoshikazu Furuta,Nina M. Donghia,Ashwin N. Ananthakrishnan,James J. Collins +11 more
TL;DR: A low-cost, paper-based synthetic biology platform that allows species-specific quantification of bacterial mRNAs and clinically relevant host biomarkers and can be used to rapidly and inexpensively detect toxin mRNA in the diagnosis of Clostridium difficile infections is presented.