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Asia Frazier
Researcher at North Shore-LIJ Health System
Publications - 3
Citations - 3529
Asia Frazier is an academic researcher from North Shore-LIJ Health System. The author has contributed to research in topics: Tumor necrosis factor alpha & Inflammation. The author has an hindex of 3, co-authored 3 publications receiving 3356 citations. Previous affiliations of Asia Frazier include New York University.
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Journal ArticleDOI
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
Haichao Wang,Ona Bloom,Minghuang Zhang,Jaideep M. Vishnubhakat,Michael Ombrellino,Jiantu Che,Asia Frazier,Huan Yang,Svetlana Ivanova,Lyudmila V. Borovikova,Kirk R. Manogue,Eugen Faist,Edward Abraham,Jan Andersson,Ulf Andersson,Patricia E. Molina,Naji N. Abumrad,Andrew E. Sama,Kevin J. Tracey +18 more
TL;DR: High mobility group-1 (HMG-1) protein was found to be released by cultured macrophages more than 8 hours after stimulation with endotoxin, TNF, or IL-1, and showed increased serum levels after endotoxin exposure, suggesting that this protein warrants investigation as a therapeutic target.
Journal ArticleDOI
Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan.
Michael Ombrellino,Haichao Wang,Huan Yang,Minghuang Zhang,Jaideep M. Vishnubhakat,Asia Frazier,Larry A. Scher,Steven G. Friedman,Kevin J. Tracey +8 more
TL;DR: A previously unrecognized anti-inflammatory role of fetuin is revealed in counter-regulating the innate immune response, and it is suggested that it may be possible to use fetuin as an experimental anti- inflammatory agent.