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Astrid Blaschitz
Researcher at University of Graz
Publications - 57
Citations - 2922
Astrid Blaschitz is an academic researcher from University of Graz. The author has contributed to research in topics: Placenta & Trophoblast. The author has an hindex of 29, co-authored 57 publications receiving 2743 citations. Previous affiliations of Astrid Blaschitz include Medical University of Graz.
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Journal ArticleDOI
The functionality of HLA-G is emerging.
TL;DR: The HLA‐G class Ib gene appears to be a functional locus and its functional properties, although incompletely understood, are likely to be important in the outcome of human pregnancies but also in normal adult life.
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Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells.
Ingrid Lang,Maria Anna Pabst,Ursula Hiden,Astrid Blaschitz,Gottfried Dohr,Tom Hahn,Gernot Desoye +6 more
TL;DR: Examination of scanning electron microscopic examination clearly showed that PLEC remained elongated at the confluent state, in contrast to the more polygonal phenotype of HPEC-A2 and HUVEC that were studied in parallel.
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Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA‐G
Astrid Blaschitz,Françoise Lenfant,Valérie Mallet,Michaele Hartmann,Armand Bensussan,Daniel E. Geraghty,Philippe Le Bouteiller,Gottfried Dohr +7 more
TL;DR: Surprisingly, BFL.1 strongly and reproducibly stained endothelial cells in the fetal capillaries present in the mesenchymal core of the chorionic villi, whereas none of the other surrounding cellular components were stained, suggesting that HLA‐G may be present as a soluble form during the whole period of fetal vascularization and/or exert a nonimmunological function related to the endothelial cell type.
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Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures.
Susanne Prattes,Gerd Hörl,Astrid Hammer,Astrid Blaschitz,Wolfgang F. Graier,Wolfgang Sattler,Rudolf Zechner,Ernst Steyrer +7 more
TL;DR: The findings identify the TGD surface layer as primary intracellular storage site for FC within adipocytes and suggest that the structural role of ER-resident proteins in this adipocyte TGD envelope has been previously neglected.
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Antibody Reaction Patterns in First Trimester Placenta: Implications for Trophoblast Isolation and Purity Screening
TL;DR: According to this study trophoblasts from first trimester placentae should be identified by cytokeratin antibodies specific for the isoform 7, and subsequent immunodepletion with antibodies to CD45RB and FSA increased the purity of the trophoblast preparation to greater than 98 per cent.