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Atanas Iliev Lalev
Researcher at University of Toronto
Publications - 3
Citations - 3366
Atanas Iliev Lalev is an academic researcher from University of Toronto. The author has contributed to research in topics: Functional genomics & Mass spectrometry. The author has an hindex of 3, co-authored 3 publications receiving 3252 citations.
Papers
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Journal ArticleDOI
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
Nevan J. Krogan,Gerard Cagney,Gerard Cagney,Haiyuan Yu,Gouqing Zhong,Xinghua Guo,Alexandr Ignatchenko,Joyce Li,Shuye Pu,Nira Datta,Aaron Tikuisis,Thanuja Punna,José M. Peregrín-Alvarez,Michael Shales,Xin Zhang,Michael Davey,Mark D. Robinson,Alberto Paccanaro,James E. Bray,Anthony Sheung,Bryan Beattie,Dawn Richards,Veronica Canadien,Atanas Iliev Lalev,Frank Mena,Peter D Wong,Andrei Starostine,Myra M. Canete,James Vlasblom,Samuel Wu,Chris Orsi,Sean R. Collins,Shamanta Chandran,Robin Haw,Jennifer J. Rilstone,Kiran Gandi,Natalie J. Thompson,Gabe Musso,Peter St Onge,Shaun Ghanny,Mandy H. Y. Lam,Gareth Butland,Amin M. Altaf-Ul,Shigehiko Kanaya,Ali Shilatifard,Erin K. O'Shea,Jonathan S. Weissman,C. James Ingles,Timothy P. Hughes,John Parkinson,Mark Gerstein,Shoshana J. Wodak,Andrew Emili,Jack Greenblatt +53 more
TL;DR: T tandem affinity purification was used to process 4,562 different tagged proteins of the yeast Saccharomyces cerevisiae to identify protein–protein interactions, which will help future studies on individual proteins as well as functional genomics and systems biology.
Journal ArticleDOI
High-Definition Macromolecular Composition of Yeast RNA-Processing Complexes
Nevan J. Krogan,Wen-Tao Peng,Gerard Cagney,Mark D. Robinson,Robin Haw,Gouqing Zhong,Xinghua Guo,Xin Zhang,Veronica Canadien,Dawn Richards,Bryan Beattie,Atanas Iliev Lalev,Wen Zhang,Armaity P. Davierwala,Sanie Mnaimneh,Andrei Starostine,Aaron Tikuisis,Jörg Grigull,Nira Datta,James E. Bray,Timothy P. Hughes,Andrew Emili,Jack Greenblatt +22 more
TL;DR: This study systematically identified and estimated the relative abundance of stably associated polypeptides and RNA species using a combination of gel densitometry, protein mass spectrometry, and oligonucleotide microarray hybridization.
Patent
Method for detecting transient ligand interactions
TL;DR: In this paper, the authors present methods and kits for separating and analyzing substoichiometrically interacting ligands from a high abundance ligand of interest in an affinity matrix system.