A
Athar Ansari
Researcher at Wayne State University
Publications - 37
Citations - 2088
Athar Ansari is an academic researcher from Wayne State University. The author has contributed to research in topics: RNA polymerase II & Transcription (biology). The author has an hindex of 19, co-authored 36 publications receiving 1944 citations. Previous affiliations of Athar Ansari include University of Medicine and Dentistry of New Jersey & Rutgers University.
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Journal ArticleDOI
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
Ronny Drapkin,Joyce T. Reardon,Athar Ansari,Juch Chin Huang,Leigh Zawel,Kyujeong Ahn,Aziz Sancar,Danny Reinberg +7 more
TL;DR: It is found thatTFIIH has a dual role, being required for basal transcription of class II genes and for participation in DNA-excision repair, and the general transcription factor IIE negatively modulates the helicase activity of TFIIH through a direct interaction between TFIIE and the ERCC3 subunit of TF IIH.
Journal ArticleDOI
A role for the CPF 3′-end processing machinery in RNAP II-dependent gene looping
Athar Ansari,Michael Hampsey +1 more
TL;DR: A model for RNAP II transcription is proposed in which promoter and terminator regions are juxtaposed, and that the resulting gene loops facilitate transcription reinitiation by the same molecule ofRNAP II in a manner dependent upon Ssu72-mediated CTD dephosphorylation.
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Characterization of the Protein Kinase Activity of TRPM7/ChaK1, a Protein Kinase Fused to the Transient Receptor Potential Ion Channel
TL;DR: Considering intracellular ion concentrations, the results suggest that, among divalent metal ions, only Mg2+ can directly modulate TRPM7/ChaK1 kinase activity in vivo.
Journal ArticleDOI
Esc1, a Nuclear Periphery Protein Required for Sir4-Based Plasmid Anchoring and Partitioning
Erik D. Andrulis,David C. Zappulla,Athar Ansari,Severine Perrod,Catherine V. Laiosa,Marc R. Gartenberg,Rolf Sternglanz +6 more
TL;DR: The data suggest that Esc1 is a component of a redundant pathway that functions to localize silencing complexes to the nuclear periphery, and that Sir protein-mediated partitioning of a telomere-based plasmid also required ESC1.
Journal ArticleDOI
SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing.
Athar Ansari,Beate Schwer +1 more
TL;DR: It is shown that SLU7 protein and a novel activity that is named SSF1 (second‐step factor 1) were required in concert with PRP16 to promote progression through the second catalytic step of splicing.