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Danny Reinberg
Researcher at New York University
Publications - 351
Citations - 73522
Danny Reinberg is an academic researcher from New York University. The author has contributed to research in topics: Chromatin & RNA polymerase II. The author has an hindex of 145, co-authored 342 publications receiving 68201 citations. Previous affiliations of Danny Reinberg include University of California, Berkeley & University of Zurich.
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Journal ArticleDOI
The Polycomb complex PRC2 and its mark in life
Raphaël Margueron,Danny Reinberg +1 more
TL;DR: This work has uncovered a role for non-coding RNA in the recruitment of PRC2 to target genes, and expanded the perspectives on its function and regulation.
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Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
TL;DR: The isolation of a multiprotein E(z) complex that contains extra sex combs, suppressor of zeste-12, and the histone binding proteins RbAp46/RbAp48 is reported, which possesses HMT activity with specificity for Lys 9 (K9) and Lys 27 (K27) of histone H3.
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Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
Yi Zhang,Danny Reinberg +1 more
TL;DR: This work aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the “building blocks” of EMT and its role in cancer progression.
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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
TL;DR: A novel polypeptide highly related to the metastasis-associated protein 1, MTA2, and the methyl-CpG-binding domain-containing protein, MBD3, were found to be subunits of the NuRD complex, which may provide a means of gene silencing by DNA methylation.
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A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
Gunnar Schotta,Monika Lachner,Kavitha Sarma,Anja Ebert,Roopsha Sengupta,Gunter Reuter,Danny Reinberg,Thomas Jenuwein +7 more
TL;DR: Together, the data indicate a function for H4-K20 trimethylation in gene silencing and further suggest H3-K9 and H4,K20 trimmedethylation as important components of a repressive pathway that can index pericentric heterochromatin.